KLHL25 antibody

Catalog No. ABIN969248

The Mouse Monoclonal anti-KLHL25 antibody has been validated for ELISA. It is suitable to detect KLHL25 in samples from Human. There are 2+ publications available.

Quick Overview for KLHL25 antibody (ABIN969248)

Target: KLHL25 (Kelch-Like 25 (KLHL25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLHL25 antibody is un-conjugated

Application: ELISA

Clone: 1B7

Product Details anti-KLHL25 Antibody

Purpose: KLHL25 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL25 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KLHL25 antibody (ABIN969248)

Lunetta, DAgostino, Karasik, Benjamin, Guo, Govindaraju, Kiel, Kelly-Hayes, Massaro, Pencina, Seshadri, Murabito: "Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S13, (2007) (PubMed).

Wiemann, Arlt, Huber, Wellenreuther, Schleeger, Mehrle, Bechtel, Sauermann, Korf, Pepperkok, Sültmann, Poustka: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, (2004) (PubMed).

Target Details for KLHL25

Target: KLHL25 (Kelch-Like 25 (KLHL25))

Alternative Name: KLHL25

Background: KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.

Molecular Weight: 65 kDa

UniProt: Q9H0H3