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Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

Antigen

Lysine (K)-Specific Demethylase 1A (KDM1A)
Synonyms AOF2, KDM1, LSD1, BHC110, KIAA0601, RP1-184J9.1, Aof2, Lsd1, AA408884, mKIAA0601, D4Ertd478e, 1810043O07Rik, RGD1562975, aof2, wu:fj36a05, KDM1A, DKFZp459N2450, kdm1, lsd1, xLSD1
Clonality Monoclonal (1B2E5)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Mouse (Murine), Monkey
Application
Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
2 references available
Catalog no. ABIN969264
Quantity 0.1ml  (Variants)
Price 341.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name LSD1/AOF2
Gene ID 23028
Immunogen Purified recombinant fragment of human LSD1 expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 1B2E5
Description The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Synonyms: KDM1, LSD1, AOF2
Molecular Weight 93kDa

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Metzger, Wissmann, Yin et al.: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).

Shi, Matson, Lan et al.: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Lysine (K)-Specific Demethylase 1A (KDM1A)", type "Antibodies"
Hosts Rabbit (44), Mouse (18)
Reactivities Human (61), Mouse (Murine) (24), Rat (Rattus) (19), Dog (Canine) (7), Monkey (7), Cow (Bovine) (4), Pig (Porcine) (2), Zebrafish (Danio rerio) (2), Cat (Feline) (1), Chicken (1), Horse (Equine) (1), Macaque (1), Mammalian (1), Primate (1), Rabbit (1)
Applications Western Blotting (WB) (63), ELISA (35), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), Immunohistochemistry (IHC) (12), Immunoprecipitation (IP) (6), Immunocytochemistry (ICC) (4), Immunofluorescence (IF) (4), Immunohistochemistry (Fixed) (IHC (fx)) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunoassay (IA) (1)
Epitopes N-Term (6), Internal Region (4), C-Term (3), AA 1-50 (1), AA 100-150 (1), AA 400-450 (1), AA 450-500 (1), AA 50-100 (1), AA 800-850 (1), Center (1), Middle Region (1)