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Details for Product No. ABIN969264

Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

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Antigen
Synonyms
AOF2, BHC110, KDM1, LSD1, 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601, RGD1562975, aof2, kdm1, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, ARABIDOPSIS LYSINE-SPECIFIC HISTONE  ... show more
Reactivity
»Alternatives Human, Mouse (Murine), Monkey
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN969264
Quantity 100 µL
Price
341.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human LSD1 expressed in E. coli.
Clone 1B2E5
Isotype IgG1
Purification Ascites
Alternative Name LSD1/AOF2
Background Synonyms:
kDaM1, LSD1, AOF2
The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, approx. 95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Molecular Weight 93 kDa
Gene ID 23028
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Metzger, Wissmann, Yin et al.: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).

Shi, Matson, Lan et al.: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, 2005 (PubMed).

Alternatives for antigen "Lysine (K)-Specific Demethylase 1A (KDM1A)", type "Antibodies"
Hosts (105), (30), (1)
Reactivities (134), (74), (59), (38), (29), (28), (24), (17), (4), (2), (2), (1), (1), (1), (1)
Applications (114), (54), (43), (21), (20), (12), (6), (5), (3), (3), (3), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (15), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
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