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Details for Product No. ABIN969302

Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibody

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Synonyms Mlc2, MLC-2, 2410014J02Rik, MLC-2v, Mlc2v, Mylpc, CMH10, MLC2, myosin, regulatory, Mlc-2
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN969302
Quantity 100 µL
319.00 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of MYL2 expressed in E. coli.
Clone 7C9
Isotype IgG1
Purification Ascites
Alternative Name MYL2
Background Synonyms:
MLC2, CMH10, DKFZp779C0562
MYL2 (myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin β (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Molecular Weight 19 kDa
Gene ID 4633
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Ueda, Murata-Hori, Tatsuka et al.: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." in: Oncogene, Vol. 21, Issue 38, pp. 5852-60, 2002 (PubMed).

Sachdev, Raychowdhury, Sarkar: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, 2004 (PubMed).

Alternatives for antigen "Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2)", type "Antibodies"
Hosts (23), (16)
Reactivities (40), (13), (10), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applications (35), (25), (10), (5), (3), (3), (3), (2), (1)
Epitopes (8), (4), (2), (2)