NR4A3 antibody

Catalog No. ABIN969434

There are 4+ publications for this product available. The Mouse Monoclonal anti-NR4A3 antibody is suitable to detect NR4A3 in samples from Human. It has been validated for ELISA.

Quick Overview for NR4A3 antibody (ABIN969434)

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NR4A3 antibody is un-conjugated

Application: ELISA

Clone: 3A5

Product Details anti-NR4A3 Antibody

Purpose: TEC Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of TEC expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-NR4A3 antibody (ABIN969434)

Jolkver, Emer, Ballan, Krämer, Eikmanns, Marin: "Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum." in: Journal of bacteriology, Vol. 191, Issue 3, pp. 940-8, (2009) (PubMed).

van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: "Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells." in: Blood, Vol. 96, Issue 10, pp. 3406-13, (2000) (PubMed).

Tsai, Chow, Chen, Huang, Hong, Jan, Kuo, Tsao, Chen, Cheng: "Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing." in: The Journal of biological chemistry, Vol. 274, Issue 14, pp. 9455-62, (1999) (PubMed).

Kitanaka, Mano, Conley, Campana: "Expression and activation of the nonreceptor tyrosine kinase Tec in human B cells." in: Blood, Vol. 91, Issue 3, pp. 940-8, (1998) (PubMed).

Target Details for NR4A3

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Alternative Name: TEC

Background: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Molecular Weight: 74 kDa

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway