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Antibodies
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anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibody
Maternal Embryonic Leucine Zipper Kinase (MELK) antibody
| Antigen |
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| Synonyms |
HPK38, KIAA0175, MPK38, AI327312, mKIAA0175, fb71b01, fe01f04, wu:fb71b01, wu:fe01f04, melk, MELK, Melk |
| Clonality |
Monoclonal (2G2) |
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Host
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Reactivity
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Application
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| Catalog no. |
ABIN969538 |
| Quantity |
0.1ml |
| Price |
396.00 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 3 to 4 Business Days |
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Alternative name
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MELK
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Gene ID
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9833
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Immunogen
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Synthesized peptide of human MELK(AA : 637-651:C-VYKRLVEDILSSCKV).
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Format
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Liquid
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Isotype
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IgG2a
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Clone
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2G2
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Description
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Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
Synonyms: HPK38
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Molecular Weight
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74.6kDa
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Application Notes
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ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
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Purification
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Purified
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Buffer
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PBS with 0.05% sodium azide and 0.5% protein stabilizer.
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Preservative
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0.05% sodium azide
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Storage
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Store at 4℃, for long term storage, store at -20℃.
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Research Area
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Embryogenesis, Embryonic stem cells, Hormones, Receptors
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Restrictions
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For Research Use only
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Product
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Pickard, Green, Ellis et al.: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, 2009 (PubMed).
Nakano, Joshi, Visnyei et al.: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, 2011 (PubMed).
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Alternatives for antigen "Maternal Embryonic Leucine Zipper Kinase (MELK)", type "Antibodies"
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Hosts
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Rabbit (34), Goat (8), Mouse (2)
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Reactivities
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Human (41), Mouse (Murine) (23), Rat (Rattus) (19), Cow (Bovine) (3), Dog (Canine) (3)
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Applications
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Western Blotting (WB) (26), ELISA (19), Immunofluorescence (IF) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (IHC) (2), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Epitopes
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C-Term (7), Internal Region (3), AA 637-651 (1), Center (1), N-Term,AA 33-62 (1)
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Alternatives 
