T Antigen (AA 218-352) antibody

Antigen: T Antigen

Binding Site: AA 218-352

Clonality: Monoclonal (6C12)

Host: Mouse

Reactivity: Human

Catalog no.: ABIN969569

Additional Information

Gene ID: 6862

Immunogen: Purified recombinant fragment of human T (AA : 218-352) expressed in E. Coli.

Format: Liquid

Isotype: IgG1

Clone: 6C12

Description: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
Synonyms: TFT

Molecular Weight: 47.4kDa

Application Details

Purification: Purified

Buffer: PBS with 0.05% sodium azide and 0.5% protein stabilizer.

Preservative: 0.05% sodium azide

Storage: Store at 4℃, for long term storage, store at -20℃.

Restrictions: For Research Use only

Publications

Product: Tirabosco, Mangham, Rosenberg et al.: "Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue." in: The American journal of surgical pathology, Vol. 32, Issue 4, pp. 572-80, 2008 (PubMed).