SECTM1 antibody (Middle Region)

Catalog No. ABIN971675

The Rabbit Polyclonal anti-SECTM1 antibody has been validated for WB. It is suitable to detect SECTM1 in samples from Human. There is 1 publication available.

Quick Overview for SECTM1 antibody (Middle Region) (ABIN971675)

Target: SECTM1 (Secreted and Transmembrane 1 (SECTM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SECTM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SECTM1 Antibody

Binding Specificity: Middle Region

Sequence: ARDSHAGLYM WHLVGHQRNN RQVTLEVSGA EPQSAPDTGF WPVPAVVTAV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SECTM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SECTM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SECTM1 antibody (ABIN971675)

Bade-Döding, Göttmann, Baigger, Farren, Lee, Blasczyk, Huyton: "Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7." in: Biochimica et biophysica acta, Vol. 1840, Issue 3, pp. 1004-13, (2014) (PubMed).

Target Details for SECTM1

Target: SECTM1 (Secreted and Transmembrane 1 (SECTM1))

Alternative Name: SECTM1

Background: This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes.
Alias Symbols: K12
Protein Interaction Partner: UBC, CD7,
Protein Size: 248

Molecular Weight: 27 kDa

Gene ID: 6398

NCBI Accession: NM_003004, NP_002995

UniProt: Q8WVN6