ABL1 antibody (pTyr245)
Quick Overview for ABL1 antibody (pTyr245) (ABIN6735184)
Target
See all ABL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr245
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Specificity
- Human c-Abl. Mouse (92% homologous) c-Abl has not been tested, but is expected to react.
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Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic phosphopeptide derived from a region of human c-Abl that contains tyrosine 245. Note: there are two widely expressed forms of c-Abl produced by alternative splicing, known as 1a and 1b (the more commonly used form). The corresponding phosphorylation site from 1a is tyrosine 226.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS (without Mg2+, Ca2+), 1 mg/mL BSA (IgG, protease free), pH 7.2, 0.1% sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.
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- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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Alternative Name
- ABL1 / C-ABL
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Background
- Standard Gene Symbol: ABL1, Gene Family: Protein Kinase, Gene Subfamily: Abl, Synonyms: ABL1, Bcr/c-abl oncogene protein, Bcr-Abl, Bcr/abl, C-ABL, ABL, JTK7, p150, Tyrosine-protein kinase ABL1, Proto-oncogene c-Abl, V-abl
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Gene ID
- 25
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UniProt
- P00519
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Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Target
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