ErbB2/Her2 antibody
Quick Overview for ErbB2/Her2 antibody (ABIN119013)
Target
See all ErbB2/Her2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody recognizes the CD340. ICR55 recognizes epitope E of CD340.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein G
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Isotype
- IgG2a
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Application Notes
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Immunohistochemistry on Frozen and Paraffin Sections. Western Blot. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Alternative Name
- CD340 / ERBB2 / HER2
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Background
- CD340 (c-erbB-2 proto-oncogene), also known as Her2/neu and c-erb B-2 is expressed at the cell surface of a range of tumour cells. In many types of tumour c-erbB-2 expression is related to poor prognosis, with an increased risk of metastasis.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2
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Gene ID
- 2064
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NCBI Accession
- NP_001005862
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UniProt
- P04626
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Target
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