You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our IL 18 Proteins (IL18)

Full name:
Interleukin 18 Proteins (IL18)
On are 76 Interleukin 18 (IL18) Proteins from 14 different suppliers available. Additionally we are shipping IL 18 Antibodies (218) and IL 18 Kits (137) and many more products for this protein. A total of 444 IL 18 products are currently listed.
ChIL-18, IGIF, IL-1g, IL-18, IL1F4, IL18
list all proteins Gene Name GeneID UniProt
IL18 16173 P70380
IL18 29197 P97636
IL18 3606 Q14116

Show all synonyms

IL 18 Proteins (IL18) by Origin

Select your origin of interest

Top referenced IL 18 Proteins

  1. Human IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN413464 : Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 4 references for ABIN413464

  2. Human IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN666748 : Yoshimoto, Takeda, Tanaka, Ohkusu, Kashiwamura, Okamura, Akira, Nakanishi: IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 references for ABIN666748

  3. Rhesus Monkey IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN2009696 : Liew, McInnes: Role of interleukin 15 and interleukin 18 in inflammatory response. in Annals of the rheumatic diseases 2002 (PubMed)

More Proteins for IL 18 Interaction Partners

Mouse (Murine) Interleukin 18 (IL18) interaction partners

  1. IL-18-elicited NK cell perforin (show PRF1 Proteins) responses seem to be critical for coordinating mucosal inflammation during early infection

  2. Data indicate that NLRC4 (show NLRC4 Proteins) activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 release, and implicate Caspase-8 (show CASP8 Proteins) in NLRC4 (show NLRC4 Proteins) inflammasome responses in vivo by generation of doubly deficient in Caspase-1 (show CASP1 Proteins) and Caspase-8 (show CASP8 Proteins).

  3. this study shows that IL-18, cooperatively with IL-23 (show IL23A Proteins), induced prominent inflammation and enhanced psoriasis-like epidermal hyperplasia

  4. telmisartan can reduce traumatic cerebral edema by inhibiting the NLRP3 (show NLRP3 Proteins) inflammasome-regulated IL-1beta (show IL1B Proteins) and IL-18 accumulation.

  5. Data, including data from studies in knockout mice, suggest that TNF (tumor necrosis factor (show TNF Proteins)), TNFR1 (show TNFRSF1A Proteins) (TNF (show TNF Proteins) receptor 1), and IL18 (interleukin 18) are involved in liver lipid metabolism. IL18 or TNFR1 (show TNFRSF1A Proteins) knockout mice on chow show higher liver triglyceride deposition than wild-type mice fed chow; in IL18 or TNFR1 (show TNFRSF1A Proteins) knockout mice, high-refined-carbohydrate diet does not lead to fatty liver disease as it does in wild-type mice.

  6. GABA-B receptor antagonists reduced Il18 levels in male mice and increased Il18 levels in female mice following neonatal hypoxia ischemia.

  7. NLRP1 is an innate immune sensor that functions in the context of metabolic stress to produce IL-18, preventing obesity and metabolic syndrome.

  8. IL-18 is sufficient to protect Birc3 (show BIRC3 Proteins)-deficient mice from sodium dodecyl sulfate-induced colitis.

  9. IL-18 plays a facilitative role via NF-kappaB (show NFKB1 Proteins) activation in pulmonary hypertension formation.

  10. IL-18 is a key epithelial-derived cytokine that differentially regulates distinct subsets of intestinal CD4 (show CD4 Proteins)(+) T cells during both homeostatic and inflammatory conditions

Pig (Porcine) Interleukin 18 (IL18) interaction partners

  1. Study reports that the monocyte-derived cytokines IL-12 (show IL12A Proteins) and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma (show IFNG Proteins) production. Additional stimuli such as the mitogen ConA and IL-2 (show IL2 Proteins) are necessary to activate the cells for enhanced proliferation.

  2. IL-18 concentration in saliva (show RAG1AP1 Proteins) was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva (show RAG1AP1 Proteins).

  3. endometrial expression of CASP1 (show CASP1 Proteins) and IL18 associated with pregnancy establishment; alteration of CASP1 (show CASP1 Proteins) and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy

  4. Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.

Human Interleukin 18 (IL18) interaction partners

  1. These results suggested that 25-HC promoted ADC cell migration and invasion in an LXR-dependent manner in the monoculture system but that in the coculture system, the 25-HC-induced IL-1beta secretion enhanced the effect of 25-HC in an LXR-independent manner.

  2. Among the NLRP3 (show NLRP3 Proteins) inflammasome genetic polymorphisms we found that the polymorphisms of IL-18 (rs1946518) and IL-1beta (show IL1B Proteins) (rs16944) were related to the clinical characteristics and may lead to poorer survival of AML (show RUNX1 Proteins) patients

  3. In summary, this meta-analysis finds that IL6 (show IL6 Proteins) rs1800795 and IL18 rs1946518 polymorphisms decrease the risk of BD. However, IL12B (show IL12B Proteins) rs3212227 increases BD susceptibility. Further large-scale investigation of this association is necessary.

  4. Letter: Suggest Il-18/Il-10 (show IL10 Proteins) SNPs may contribute to genetic susceptibility to oral lichen planus and to development of erosive phenotype.

  5. Low IL18 expression is associated with malignant melanoma.

  6. Suggest that the IL18 gene may have a significant relationship with triglyceride and LDL cholesterol levels in peripheral arterial disease patients.

  7. Study demonstrates that the expression of the NLRP3 (show NLRP3 Proteins)-caspase-1 (show CASP1 Proteins)-IL-18 axis is highly expressed in the peripheral blood mononuclear cells of patients with bullous pemphigoid (show DST Proteins) (BP), and correlated with disease activity, suggesting its involvement in the pathogenesis and progression of BP.

  8. Serum IL-18 levels were significantly higher in patients with IL-18-137 GG and IL-18-607 CC genotypes before renal transplantation. The influence of these polymorphisms on oxidative stress has not been observed.

  9. Furthermore, the correlation between the IL-18 -137G/C polymorphism and HCC (show FAM126A Proteins)-related HBV infection is a risk factor for vascular invasion and has a synergistic effect that can further enhance HCC (show FAM126A Proteins) prognosis.

  10. IL-18 is associated with inflammatory activity in gout, as well as with IL-6 (show IL6 Proteins) levels.

Cow (Bovine) Interleukin 18 (IL18) interaction partners

  1. These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.

Rabbit Interleukin 18 (IL18) interaction partners

  1. Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP (show IL18BP Proteins).

IL 18 (IL18) Protein Profile

Protein Summary

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IL 18 (IL18)

  • interleukin 18 (Il18)
  • interleukin 18 (interferon-gamma-inducing factor) (IL18)
  • interleukin-18 (Il-18)
  • ChIL-18 protein
  • IGIF protein
  • IL-1g protein
  • IL-18 protein
  • IL1F4 protein
  • IL18 protein

Protein level used designations for Interleukin 18 Proteins (IL18)

IFN-gamma-inducing factor , IL-1 gamma , interferon gamma-inducing factor , interferon-gamma-inducing factor , interleukin-1 gamma , interleukin-18 , IL-18 , interferon gamma inducing factor , iboctadekin , Interferon gamma-inducing factor , Interleukin-18 , interleukin 18 , uncharacterized protein LOC100734451

16173 Mus musculus
29197 Rattus norvegicus
397057 Sus scrofa
403796 Canis lupus familiaris
395312 Gallus gallus
3606 Homo sapiens
281249 Bos taurus
100861190 Capra hircus
100034216 Equus caballus
100144338 Oryctolagus cuniculus
493688 Felis catus
443206 Ovis aries
100734451 Cavia porcellus
Selected quality suppliers for IL 18 Proteins (IL18)
Did you look for something else?