Browse our IL 18 Proteins (IL18)

Full name:
Interleukin 18 Proteins (IL18)
On www.antibodies-online.com are 80 Interleukin 18 (IL18) Proteins from 14 different suppliers available. Additionally we are shipping IL 18 Antibodies (241) and IL 18 Kits (148) and many more products for this protein. A total of 481 IL 18 products are currently listed.
Synonyms:
ChIL-18, IGIF, IL-1g, IL-18, IL1F4, IL18
list all proteins Gene Name GeneID UniProt
IL18 16173 P70380
IL18 29197 P97636
IL18 3606 Q14116

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IL 18 Proteins (IL18) by Origin

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Top referenced IL 18 Proteins

  1. Human IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN413464 : Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 4 references for 413464

  2. Human IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN666748 : Yoshimoto, Takeda, Tanaka, Ohkusu, Kashiwamura, Okamura, Akira, Nakanishi: IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 references for 666748

  3. Rhesus Monkey IL 18 Protein expressed in Escherichia coli (E. coli) - ABIN2009696 : Liew, McInnes: Role of interleukin 15 and interleukin 18 in inflammatory response. in Annals of the rheumatic diseases 2002 (PubMed)

More Proteins for IL 18 Interaction Partners

Mouse (Murine) Interleukin 18 (IL18) interaction partners

  1. study found that IL-18 and IL-1beta (show IL1B Proteins) are differentially regulated. Despite being constitutively expressed, IL-18 expression was increased and sustained after stimulation of TLRs. In contrast, IL-1beta (show IL1B Proteins) was induced but not sustained after chronic treatment.

  2. the GLA (show GLA Proteins)-SE adjuvant operates through interaction with IL-18-producing SCMsmall ef, Cyrillic for the rapid induction of B cell expansion and differentiation, Ab secretion, and Th1 (show HAND1 Proteins) responses

  3. IL-18 is essentially involved in mediating C. jejuni infection in the gnotobiotic mouse model.

  4. These results demonstrate a central role for the AIM2 (show AIM2 Proteins) inflammasome in preventing dysbiosis and intestinal inflammation through regulation of the IL-18/IL-22BP (show IL22RA2 Proteins)/IL-22 (show IL22 Proteins) and STAT3 (show STAT3 Proteins) pathway

  5. Aldosterone induced IL-18 gene expression in renal tubular epithelial cells in a concentration- and time-dependent manner.

  6. this study demonstrated the critical function of IL-18 in lipid metabolism and these findings might contribute to the progress of novel treatments for nonalcoholic fatty liver disease or nonalcoholic steatohepatitis.

  7. Results indicated that IL-18 has roles apart from those as a proinflammatory cytokine in cardiac myocytes and suggested that IL-18 contributes to the homeostatic maintenance of mitochondrial function and gap-junction turnover in cardiac myocytes, possibly by upregulating autophagy.

  8. IL-18-elicited NK cell perforin (show PRF1 Proteins) responses seem to be critical for coordinating mucosal inflammation during early infection

  9. Data indicate that NLRC4 (show NLRC4 Proteins) activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 release, and implicate Caspase-8 (show CASP8 Proteins) in NLRC4 (show NLRC4 Proteins) inflammasome responses in vivo by generation of doubly deficient in Caspase-1 (show CASP1 Proteins) and Caspase-8 (show CASP8 Proteins).

  10. this study shows that IL-18, cooperatively with IL-23 (show IL23A Proteins), induced prominent inflammation and enhanced psoriasis-like epidermal hyperplasia

Pig (Porcine) Interleukin 18 (IL18) interaction partners

  1. Study reports that the monocyte-derived cytokines IL-12 (show IL12A Proteins) and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma (show IFNG Proteins) production. Additional stimuli such as the mitogen ConA and IL-2 (show IL2 Proteins) are necessary to activate the cells for enhanced proliferation.

  2. IL-18 concentration in saliva (show RAG1AP1 Proteins) was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva (show RAG1AP1 Proteins).

  3. endometrial expression of CASP1 (show CASP1 Proteins) and IL18 associated with pregnancy establishment; alteration of CASP1 (show CASP1 Proteins) and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy

  4. Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice.

Human Interleukin 18 (IL18) interaction partners

  1. IL-18 SNPs were associated with pulmonary tuberculosis with co-morbid diabetes in patients and their household contacts.

  2. this study shows il-18 restores the phosphoantigen response of Vgamma9Vdelta2+ T cells from HIV-positive individuals on antiretroviral therapy

  3. IL-18, IL-18R and IL-18BP (show IL18BP Proteins) expression in eosinophil are involved in the inflammatory reaction of asthma.

  4. Patients with NLRP1-associated autoinflammation with arthritis and dyskeratosis syndrome had increased systemic IL18.

  5. Genetic polymorphisms within the FUCA2 (show FUCA2 Proteins) and IL18 gene regions are also associated with diastolic function in SCD (show SCD Proteins), likely by affecting expression levels of the genes

  6. rs187238, rs360719, and rs549908 in IL-18 are associated with reduced risk of atrial fibrillation in Chinese patients.

  7. The biochemical function of NLPR3 inflammasomes is to activate caspase-1 (show CASP1 Proteins), which leads to the maturation of interleukin 1 beta (show IL1B Proteins) and IL-18 and the induction of pyroptosis, a form of cell death. (Review)

  8. The IL-18-607A/C polymorphism may not contribute directly to the susceptibility to schizophrenia. This polymorphism is associated with clinical psychopathology of schizophrenia patients. Interaction of increased serum level of IL-18 and the IL-18-607A/C polymorphism affects the clinical psychopathological symptoms

  9. Genetic variation in IL-18 is associated with IL-18 production in response to HIV and HCV infection, and may explain variability in the inflammatory outcomes of chronic viral infections.

  10. IL18-607C>A and IL18-137G>C genetic polymorphisms seem to influence depression relapse after antidepressant treatment in our subset of depressed patients, and may possibly contribute to the disregulated IL-18 levels found in patients with depression.

Cow (Bovine) Interleukin 18 (IL18) interaction partners

  1. These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.

Rabbit Interleukin 18 (IL18) interaction partners

  1. Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP (show IL18BP Proteins).

IL 18 (IL18) Protein Profile

Protein Summary

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IL 18 (IL18)

  • interleukin 18 (Il18)
  • interleukin 18 (interferon-gamma-inducing factor) (IL18)
  • interleukin-18 (Il-18)
  • ChIL-18 protein
  • IGIF protein
  • IL-1g protein
  • IL-18 protein
  • IL1F4 protein
  • IL18 protein

Protein level used designations for Interleukin 18 Proteins (IL18)

IFN-gamma-inducing factor , IL-1 gamma , interferon gamma-inducing factor , interferon-gamma-inducing factor , interleukin-1 gamma , interleukin-18 , IL-18 , interferon gamma inducing factor , iboctadekin , Interferon gamma-inducing factor , Interleukin-18 , interleukin 18 , uncharacterized protein LOC100734451

GENE ID SPECIES
16173 Mus musculus
29197 Rattus norvegicus
397057 Sus scrofa
403796 Canis lupus familiaris
395312 Gallus gallus
3606 Homo sapiens
281249 Bos taurus
100861190 Capra hircus
100034216 Equus caballus
100144338 Oryctolagus cuniculus
493688 Felis catus
443206 Ovis aries
100734451 Cavia porcellus
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