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Browse our anti-LAT2 (LAT2) Antibodies

Full name:
anti-Linker For Activation of T Cells Family, Member 2 Antibodies (LAT2)
On www.antibodies-online.com are 160 Linker For Activation of T Cells Family, Member 2 (LAT2) Antibodies from 20 different suppliers available. Additionally we are shipping LAT2 Proteins (22) and many more products for this protein. A total of 191 LAT2 products are currently listed.
Synonyms:
AW125574, BG:DS00004.9, CG1264, Dmel\\CG1264, Dmlab, Dm lab, EfR9, F24, F90, F90-2, F121, l(3)01241, l(3)84Ac, LAB, LAT2, lb, MGC139435, Ntal, Wbscr5, Wbscr15, WSCR5

Most Popular Reactivities for anti-LAT2 (LAT2) Antibodies

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anti-Human LAT2 Antibodies:

anti-Mouse (Murine) LAT2 Antibodies:

anti-Rat (Rattus) LAT2 Antibodies:

All available anti-LAT2 Antibodies

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Top referenced anti-LAT2 Antibodies

  1. Human Monoclonal LAT2 Primary Antibody for ICC, FACS - ABIN94439 : Duque-Afonso, Yalcin, Berg, Abdelkarim, Heidenreich, Lübbert: The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO. in Oncogene 2011 (PubMed)
    Show all 6 references for ABIN94439

  2. Mouse (Murine) Polyclonal LAT2 Primary Antibody for IF, WB - ABIN238345 : Horejsí, Zhang, Schraven: Transmembrane adaptor proteins: organizers of immunoreceptor signalling. in Nature reviews. Immunology 2004 (PubMed)
    Show all 5 references for ABIN238345

  3. Human Polyclonal LAT2 Primary Antibody for EIA, WB - ABIN953143 : Rieke, Kähne, Schweitzer, Schraven, Wienands, Engelke, Naumann: Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells. in Cellular signalling 2009 (PubMed)
    Show all 5 references for ABIN953143

  4. Mouse (Murine) Polyclonal LAT2 Primary Antibody for ICC, WB - ABIN125755 : Yamasaki, Ishikawa, Sakuma, Kanagawa, Cheng, Malissen, Saito: LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival. in Molecular and cellular biology 2007 (PubMed)
    Show all 5 references for ABIN125755

  5. Human Monoclonal LAT2 Primary Antibody for FACS - ABIN94440 : Brdicka, Imrich, Angelisová, Brdicková, Horváth, Spicka, Hilgert, Lusková, Dráber, Novák, Engels, Wienands, Simeoni, Osterreicher, Aguado, Malissen, Schraven, Horejsí: Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling. in The Journal of experimental medicine 2002 (PubMed)
    Show all 4 references for ABIN94440

  6. Human Polyclonal LAT2 Primary Antibody for IHC (p), WB - ABIN238343 : Tkaczyk, Horejsi, Iwaki, Draber, Samelson, Satterthwaite, Nahm, Metcalfe, Gilfillan: NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation. in Blood 2004 (PubMed)
    Show all 3 references for ABIN238343

  7. Mouse (Murine) Polyclonal LAT2 Primary Antibody for WB - ABIN238344 : Volná, Lebduska, Dráberová, Símová, Heneberg, Boubelík, Bugajev, Malissen, Wilson, Horejsí, Malissen, Dráber: Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL. in The Journal of experimental medicine 2004 (PubMed)
    Show all 3 references for ABIN238344

More Antibodies against LAT2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. labial protein (show HOXD1 Antibodies) was expressed in adult labk3/labvd1 copper cells, but not in larvae

  2. Labial, Ultrabithorax, Antennapedia, Extradenticle and Homothorax (show MEIS1 Antibodies) are regulated in a signal transduction pathway in developing Drosophila brain

Human Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. The detergent-induced stabilization of the purified human 4F2hc (show SLC3A2 Antibodies)-LAT2 complex presented here paves the way towards its crystallization and structure determination at high-resolution

  2. The AML1 (show RUNX1 Antibodies)/ETO (show RUNX1T1 Antibodies) target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells.

  3. LAT2 is an early mediator of the anti-leukemic activity of alkylphospholipids and arsenic trioxide. Thus, LAT2 may be used as a target for the design of drugs for cancer therapy.

  4. NTAL acts as a tumor suppressor that enhances the proximal signaling of leukemic blasts. The key downstream molecule responsible for the biological effect of TCR signaling is ERK (show EPHB2 Antibodies).

  5. LAT2 protein (NTAL) participates in the activation of the c-Met-Grb2 (show GRB2 Antibodies)-ERK (show EPHB2 Antibodies)-cPLA2 (show PLA2G4A Antibodies) signalling cascade at early stages of H. pylori infection.

  6. data show that NTAL (non-T cell activation linker) appears to be a structural and possibly also functional homologue of LAT (linker for activation of T cells (show LAT Antibodies))in non-T cells [non-T cell activation linker]

  7. LAB links BCR (show BCR Antibodies) engagement to downstream signaling pathways.

  8. LAB was primarily phosphorylated on three membrane-distal tyrosines, Tyr (show TYR Antibodies)(136), Tyr (show TYR Antibodies)(193), and Tyr (show TYR Antibodies)(233). Mutation of these three tyrosines abolished Grb2 (show GRB2 Antibodies) binding and LAB function

  9. LAB resembled a LAT (show ORC3 Antibodies) molecule unable to bind phospholipase C (show PLC Antibodies)-gamma1.

  10. The NTAL/LAB is expressed in a variety of immune cells.

Mouse (Murine) Linker For Activation of T Cells Family, Member 2 (LAT2) interaction partners

  1. NTAL is a negative regulator of FcepsilonRI (show FCER1A Antibodies) activation events in murine bone marrow-derived mast cells, independently of possible compensatory developmental alterations.

  2. Cerebral cortex hyperthyroidism of newborn mct8 (show MCT8 Antibodies)-deficient mice transiently suppressed by lat2 (show SLC7A8 Antibodies) inactivation.

  3. Our data define a novel link between LAB and beta-catenin (show CTNNB1 Antibodies) nuclear accumulation in dendritic cells that facilitates IFN-gamma (show IFNG Antibodies) responses during anti-fungal immunity

  4. chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI (show FCER1A Antibodies), tetraspanin CD9 (show CD9 Antibodies), transmembrane adaptor proteins NTAL and LAT (show LAT Antibodies), and cytoskeleton-regulatory proteins of the ERM (show ETV5 Antibodies) family

  5. Dihydrotestosterone treatment increased the expression of LAT2 (show SLC7A8 Antibodies).

  6. The expression of Mct8 (show MCT8 Antibodies) and L-type amino acid transporters Lat2 (show SLC7A8 Antibodies) and Lat1 (show SLC7A5 Antibodies) are determined in brain neurons during development.

  7. a crucial role of NTAL in signaling, via RhoA (show RHOA Antibodies), to mast cell cytoskeleton.

  8. While SLP-76 (show LCP2 Antibodies) and LAT1 (show SLC7A5 Antibodies) depend on each other for many of their functions, LAT2 (show SLC7A8 Antibodies)/SLP-76 (show LCP2 Antibodies) interactions and SLP-76 (show LCP2 Antibodies)-independent LAT1 (show SLC7A5 Antibodies) functions also mediate a positive signaling pathway downstream of FcepsilonRI (show FCER1A Antibodies) in mast cells.

  9. LAB is a critical, LAT (show LAT Antibodies)-independent regulator of TREM-2 (show TREM2 Antibodies) signaling and macrophage development capable of controlling subsequent inflammatory responses

  10. NTAL negatively regulates Fc-epsilon receptor I-mediated signaling events in bone marrow-derived mast cells.

LAT2 Antigen Profile

Antigen Summary

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.

Alternative names and synonyms associated with LAT2

  • labial (lab) antibody
  • linker for activation of T cells family, member 2 (LAT2) antibody
  • linker for activation of T cells family, member 2 (Lat2) antibody
  • AW125574 antibody
  • BG:DS00004.9 antibody
  • CG1264 antibody
  • Dmel\\CG1264 antibody
  • Dmlab antibody
  • Dm lab antibody
  • EfR9 antibody
  • F24 antibody
  • F90 antibody
  • F90-2 antibody
  • F121 antibody
  • l(3)01241 antibody
  • l(3)84Ac antibody
  • LAB antibody
  • LAT2 antibody
  • lb antibody
  • MGC139435 antibody
  • Ntal antibody
  • Wbscr5 antibody
  • Wbscr15 antibody
  • WSCR5 antibody

Protein level used designations for LAT2

CG1264-PA , CG1264-PB , lab-PA , lab-PB , linker for activation of T cells family, member 2 , L-type amino acid transporter subunit , Williams-Beuren syndrome chromosomal region 15 protein , Williams-Beuren syndrome chromosomal region 5 protein , linker for activation of B-cells , linker for activation of T cells, transmembrane adaptor 2 , linker for activation of T-cells family member 2 , membrane-associated adapter molecule , non-T-cell activation linker , Williams-Beuren syndrome chromosome region 15 homolog , Williams-Beuren syndrome chromosome region 5 homolog , non-T cell activation linker , williams-Beuren syndrome chromosomal region 15 protein homolog , Williams-Beuren syndrome chromosome region 5-like protein

GENE ID SPECIES
40817 Drosophila melanogaster
443250 Ovis aries
505016 Bos taurus
607740 Canis lupus familiaris
7462 Homo sapiens
56743 Mus musculus
317676 Rattus norvegicus
417489 Gallus gallus
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