Browse our anti-PDGFRB (PDGFRB) Antibodies

Full name:
anti-Platelet-Derived Growth Factor Receptor, beta Polypeptide Antibodies (PDGFRB)
On www.antibodies-online.com are 586 Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) Antibodies from 33 different suppliers available. Additionally we are shipping PDGFRB Kits (44) and PDGFRB Proteins (41) and many more products for this protein. A total of 713 PDGFRB products are currently listed.
Synonyms:
AI528809, CD140B, IBGC4, JTK12, PDGFR, PDGFR-1, PDGFR1
list all antibodies Gene Name GeneID UniProt
PDGFRB 18596 P05622
PDGFRB 24629 Q05030
PDGFRB 5159 P09619

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All available anti-PDGFRB Antibodies

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Top referenced anti-PDGFRB Antibodies

  1. Human Monoclonal PDGFRB Primary Antibody for IF, IHC (p) - ABIN111188 : Hart, Seifert, Ross, Bowen-Pope: Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody. in The Journal of biological chemistry 1987 (PubMed)
    Show all 3 references for 111188

  2. Human Monoclonal PDGFRB Primary Antibody for IHC (f), WB - ABIN967593 : Claesson-Welsh: Platelet-derived growth factor receptor signals. in The Journal of biological chemistry 1995 (PubMed)
    Show all 3 references for 967593

  3. Human Polyclonal PDGFRB Primary Antibody for EIA, IHC (p) - ABIN359922 : Wu, Windmiller, Wang, Backer: YXXM motifs in the PDGF-beta receptor serve dual roles as phosphoinositide 3-kinase binding motifs and tyrosine-based endocytic sorting signals. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 359922

  4. Human Polyclonal PDGFRB Primary Antibody for IF, IHC - ABIN1532388 : Wilkinson, Velloso, Lopes, Lee, Aster, Shipp, Aguiar: Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib. in Blood 2003 (PubMed)

  5. Human Polyclonal PDGFRB Primary Antibody for ELISA, WB - ABIN1532640 : Chi, McPhee, Wagner, Dietz, Pantazis, Goustin: Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity. in Oncogene 1997 (PubMed)

  6. Human Polyclonal PDGFRB Primary Antibody for IF, IHC - ABIN1532980 : Yu, Zeidel, Hill: Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast. in PLoS ONE 2012 (PubMed)

More Antibodies against PDGFRB Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) interaction partners

  1. Identify PDGFRbeta as a driver in activating Akt (show AKT1 Antibodies)/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  2. Data show that three platelet-derived growth factor receptor beta (PDGFRB) mutants (R561C, P660T and N666K) were able to transform NIH3T3 and Ba/F3 cells to different extents.

  3. data therefore collectively suggest that upon TGFbeta (show TGFB1 Antibodies) stimulation, SP1 (show SP1 Antibodies) recruits SMAD2 (show SMAD2 Antibodies) to the promoter of Pdgfrb to up-regulate its expression and thus Pdgfrb is a direct downstream target of the TGFbeta (show TGFB1 Antibodies)/SMAD2 (show SMAD2 Antibodies) signaling

  4. PdgfrbetaF7/F7 mice between 4-6 and 36-48 weeks of age developed a region-dependent loss in pericyte coverage (22-46, 24-44 and 4-31%) and cell numbers (36-49, 34-64 and 11-36%), reduction in capillary length (20-39, 13-46 and 1-30%), and an increase in extravascular fibrinogen-derived deposits (3.4-5.2, 2.8-4.1 and 0-3.6-fold) demonstrating BBB (show ALMS1 Antibodies) breakdown in the cortex, hippocampus and thalamus, respectively.

  5. PDGF-B (show PDGFB Antibodies)-PDGFRbeta signaling plays a significant role in the development of adipose tissue neovascularization.

  6. there is great possibility that EPCs overexpressing PDGFR-beta enhanc VSMC apoptosis and suppress VSMC migration by competitive consumption of PDGF (show PDGFA Antibodies)-BB in the early phase after carotid artery injury in mice.

  7. PDGFRalpha and PDGFRbeta are coexpressed in the craniofacial mesenchyme of mid-gestation mouse embryos and that ablation of Pdgfrb in the neural crest lineage results in increased nasal septum width, delayed palatal shelf development, and subepidermal blebbing.

  8. The results from this study indicate that PDGF (show PDGFA Antibodies) signaling is required for fiber hypertrophy, extracellular matrix production, and angiogenesis that occur during muscle growth.

  9. Data show that oligodendrocyte transcription factor 2 (Olig2 (show OLIG2 Antibodies)) deletion causes platelet-derived growth factor receptor (PDGFR) downregulation and reciprocal epidermal growth factor receptor (EGFR (show EGFR Antibodies)) upregulation.

  10. Decreased expression of PDGFR-beta in vascular smooth muscle cells was associated with thrombosis in vivo.

Human Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) interaction partners

  1. Identify PDGFRbeta as a driver in activating Akt (show AKT1 Antibodies)/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  2. Higher expression of PDGFR-Beta is related to more serious dural penetration of clival chordomas.

  3. Targeted next-generation DNA sequencing identified PDGFRB alterations in all cases of myopericytomatosis and conventional myopericytoma tested (5 cases each), including mutations in 4 cases of myopericytomatosis (N666K in 3; Y562-R565 deletion in 1 case) and 3 myopericytomas (Y562C, K653E, and splice acceptor deletion in 1 case each), as well as low-level PDGFRB amplification in 2 cases of myopericytomatosis and 4 myoperi

  4. Elevated PDGFRB expression was noted in 20.7% of patients with papillary renal cell carcinoma (show MOK Antibodies).

  5. Imatinib in myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRB in chronic or blast phase

  6. inhibition of any internalization mechanism impaired activation of STAT3 (show STAT3 Antibodies) but not of other downstream effectors of PDGFRbeta.

  7. this is the first study reporting apparently somatic recurrent PDGFRB mutations as molecular driver events in the majority of sporadic infantile and adult solitary myofibromas

  8. results demonstrate that miR (show MLXIP Antibodies)-9 and miR (show MLXIP Antibodies)-200 play opposite roles in the regulation of the vasculogenic ability of triple-negative breast cancer, acting as facilitator and suppressor of PDGFRbeta, respectively

  9. Among 15 childhood ALL patients with EBF1 (show EBF1 Antibodies)-PDGFRB fusion proteins, the fusion arose from interstitial deletion of 5q33 (n = 11), balanced rearrangement (n = 2), or complex rearrangement (n = 2).

  10. Previously unrecognised associations between renal cell carcinoma (show MOK Antibodies) survival and the absolute levels, and variability, of perivascular PDGFR-beta.

PDGFRB Antigen Profile

Antigen Summary

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor\; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Alternative names and synonyms associated with PDGFRB

  • platelet derived growth factor receptor, beta polypeptide (Pdgfrb) antibody
  • platelet-derived growth factor receptor, beta polypeptide (PDGFRB) antibody
  • AI528809 antibody
  • CD140B antibody
  • IBGC4 antibody
  • JTK12 antibody
  • PDGFR antibody
  • PDGFR-1 antibody
  • PDGFR1 antibody

Protein level used designations for PDGFRB

CD140 antigen-like family member B , PDGF beta chain , PDGF-R-beta , PDGFR-beta , beta platelet-derived growth factor receptor , beta-type platelet-derived growth factor receptor , platelet-derived growth factor receptor 1 , platelet-derived growth factor receptor beta , platelet-derived growth factor receptor beta variant 1 , Platelet-derived growth factor receptor, beta , protein tyrosin kinase

GENE ID SPECIES
18596 Mus musculus
24629 Rattus norvegicus
5159 Homo sapiens
442985 Canis lupus familiaris
770488 Gallus gallus
100342872 Oryctolagus cuniculus
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