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Browse our IL-13 Proteins (IL13)

Full name:
Interleukin 13 Proteins (IL13)
On are 120 Interleukin 13 (IL13) Proteins from 20 different suppliers available. Additionally we are shipping IL-13 Antibodies (359) and IL-13 Kits (163) and many more products for this protein. A total of 661 IL-13 products are currently listed.
Il-13, IL13, L13, P600
list all proteins Gene Name GeneID UniProt
IL13 3596 P35225
IL13 16163 P20109
IL13 116553 P42203

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IL-13 Proteins (IL13) by Origin

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Top referenced IL-13 Proteins

  1. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2667457 : Harris, De Haro, Master, Keane, Roberts, Delgado, Deretic: T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. in Immunity 2007 (PubMed)
    Show all 6 references for ABIN2667457

  2. Human IL-13 Protein expressed in Human Cells - ABIN2002687 : Minty, Chalon, Derocq, Dumont, Guillemot, Kaghad, Labit, Leplatois, Liauzun, Miloux: Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. in Nature 1993 (PubMed)
    Show all 5 references for ABIN2002687

  3. Mouse (Murine) IL-13 Protein expressed in Human Cells - ABIN2007534 : Sironi, Sciacca, Matteucci, Conni, Vecchi, Bernasconi, Minty, Caput, Ferrara, Colotta: Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. in Blood 1994 (PubMed)
    Show all 5 references for ABIN2007534

  4. Human IL-13 Protein expressed in CHO Cells - ABIN2002689 : Solymar, Agarwal, Bassing, Alt, Rao: A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. in Immunity 2002 (PubMed)
    Show all 5 references for ABIN2002689

  5. Cynomolgus IL-13 Protein expressed in Human Cells - ABIN2003834 : Monticelli, Solymar, Rao: Role of NFAT proteins in IL13 gene transcription in mast cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN2003834

  6. Human IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2666703 : LaPorte, Juo, Vaclavikova, Colf, Qi, Heller, Keegan, Garcia: Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. in Cell 2008 (PubMed)
    Show all 5 references for ABIN2666703

  7. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN1305069 : Doherty, Kastelein, Menon, Andrade, Coffman: Modulation of murine macrophage function by IL-13. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
    Show all 3 references for ABIN1305069

More Proteins for IL-13 Interaction Partners

Human Interleukin 13 (IL13) interaction partners

  1. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Proteins) and IL-13, down-regulates matriptase (show ST14 Proteins) as well as prostasin (show PRSS8 Proteins) through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Proteins)

  2. investigated the role of six potentially functional variants of the IL4 (show IL4 Proteins), IL13, and IL4R (show IL4R Proteins) genes in gastrointestinal cancer; both IL13 rs20541 and rs1800925 were not associated with gastrointestinal cancer risk for any of the genetic models and subgroup analyses [meta-analysis]

  3. IL13 in bronchial epithelial cells and bronchial alveolar lavage fluid, rather than RAD50 (show RAD50 Proteins), IL4 (show IL4 Proteins), or IL5 (show IL5 Proteins), is more likely to be the asthma susceptibility gene.

  4. We also found that the activation of H4R (show HRH4 Proteins) caused the release of IL-13 and RANTES (show CCL5 Proteins) on human mast cells.these data demonstrate that the H4R (show HRH4 Proteins) activates divergent signaling pathways to induce cytokine and chemokine (show CCL1 Proteins) production in human mast cells

  5. IL13 Arg130Gln genotypes can play a role in genetic susceptibility to allergy via regulation of serum total IgE levels and affecting IFN-gamma (show IFNG Proteins) gene expression.

  6. The GG genotype of IL-13 130A/G cytokine gene might be involved in the induced production of total IgE and IL-13 cytokine serum levels suggesting IL-13 may be important in the signalling of asthma.

  7. STAT6 (show STAT6 Proteins)-TMEM16A (show ANO1 Proteins)-ERK1/2 signal pathway and TMEM16A (show ANO1 Proteins) channel activity are required for the IL-13-induced TMEM16A (show ANO1 Proteins) mediated mucus production

  8. TGF-beta (show TGFB1 Proteins)- and IL-13-producing mast cells might be key players in the development of bone marrow fibrosis.

  9. this study shows that low expression of tristetraprolin (show ZFP36 Proteins) is associated with glioma growth and metastasis by targeting IL-13

  10. this study shows that IL-13 gene polymorphism is associated with allergic rhinitis and/or allergic conjunctivitis in Finnish asthma patients

Mouse (Murine) Interleukin 13 (IL13) interaction partners

  1. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Proteins) and IL-13, down-regulates matriptase (show ST14 Proteins) as well as prostasin (show PRSS8 Proteins) through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Proteins)

  2. These data demonstrate that multiple pathogenic strains of RSV induce IL-13-producing group 2 innate lymphoid cell proliferation and activation through a TSLP (show TSLP Proteins)-dependent mechanism in a murine model and suggest the potential therapeutic targeting of TSLP (show TSLP Proteins) during severe RSV infection.

  3. The soluble antigen from A. cantonensis could promote the Chil3 expression in macrophage and microglial cell lines induced by interleukin-13.

  4. The reduction in fibrosis observed when IL-13 signalling is suppressed is not dependent on increased IFN-gamma (show IFNG Proteins) activity. Instead, by reducing compensatory increases in type 1-associated inflammation, therapeutic strategies that block IFN-gamma (show IFNG Proteins) and IL-13 activity simultaneously can confer greater protection from progressive fibrosis than IL-13 blockade alone.

  5. Ellagic acid treatment augmented specific IL-10 (show IL10 Proteins) production in response to S. mansoni antigenic stimulation. However, specific IL-1beta (show IL1B Proteins), IL-4 (show IL4 Proteins), IL-12 (show IL12A Proteins), IL-13, IL-17A (show IL17A Proteins), TNF-alpha (show TNF Proteins) and IFN-gamma (show IFNG Proteins) production were significantly reduced with ex vivo and in vivo ellagic acid treatment.

  6. The IL-23/IL-17 axis plays a critical role in the immunopathology of hepatic amebiasis. IL-13 secreted by CD11b(+)Ly6C(lo) monocytes may be associated with recovery from liver damage.

  7. PLD1 activation enhanced binding of ROCK1 (show ROCK1 Proteins) to ATF-2 (show ATF2 Proteins) and leads to increased expression of IL-13

  8. Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis.

  9. IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.

  10. Placenta growth factor (show PGF Proteins) augments airway hyperresponsiveness via leukotrienes and IL-13.

Cow (Bovine) Interleukin 13 (IL13) interaction partners

  1. T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Proteins) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.

IL-13 (IL13) Protein Profile

Protein Summary

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Alternative names and synonyms associated with IL-13 (IL13)

  • interleukin 13 (IL13)
  • interleukin 13 (Il13)
  • interleukin-13 (IL-13)
  • Il-13 protein
  • IL13 protein
  • L13 protein
  • P600 protein

Protein level used designations for Interleukin 13 Proteins (IL13)

interleukin 13 , interleukin-13 , T-cell activation protein P600 , IL-13

100137221 Papio anubis
3596 Homo sapiens
16163 Mus musculus
100720118 Cavia porcellus
116553 Rattus norvegicus
396721 Sus scrofa
281247 Bos taurus
442990 Canis lupus familiaris
574325 Macaca mulatta
664707 Ovis aries
474361 Gallus gallus
449564 Pan troglodytes
100034113 Equus caballus
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