Browse our IL-13 Proteins (IL13)

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Interleukin 13 Proteins (IL13)
On are 136 Interleukin 13 (IL13) Proteins from 22 different suppliers available. Additionally we are shipping IL-13 Antibodies (368) and IL-13 Kits (162) and many more products for this protein. A total of 685 IL-13 products are currently listed.
Il-13, IL13, L13, P600
list all proteins Gene Name GeneID UniProt
IL13 3596 P35225
IL13 16163 P20109
IL13 116553 P42203

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IL-13 Proteins (IL13) by Origin

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Top referenced IL-13 Proteins

  1. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2667457 : Harris, De Haro, Master, Keane, Roberts, Delgado, Deretic: T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. in Immunity 2007 (PubMed)
    Show all 6 references for 2667457

  2. Human IL-13 Protein expressed in Human Cells - ABIN2002687 : Minty, Chalon, Derocq, Dumont, Guillemot, Kaghad, Labit, Leplatois, Liauzun, Miloux: Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. in Nature 1993 (PubMed)
    Show all 5 references for 2002687

  3. Cynomolgus IL-13 Protein expressed in Human Cells - ABIN2003834 : Sironi, Sciacca, Matteucci, Conni, Vecchi, Bernasconi, Minty, Caput, Ferrara, Colotta: Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. in Blood 1994 (PubMed)
    Show all 5 references for 2003834

  4. Mouse (Murine) IL-13 Protein expressed in Human Cells - ABIN2007534 : Solymar, Agarwal, Bassing, Alt, Rao: A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. in Immunity 2002 (PubMed)
    Show all 5 references for 2007534

  5. Human IL-13 Protein expressed in CHO Cells - ABIN2002689 : Monticelli, Solymar, Rao: Role of NFAT proteins in IL13 gene transcription in mast cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 2002689

  6. Human IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2666703 : LaPorte, Juo, Vaclavikova, Colf, Qi, Heller, Keegan, Garcia: Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. in Cell 2008 (PubMed)
    Show all 5 references for 2666703

  7. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN1305069 : Doherty, Kastelein, Menon, Andrade, Coffman: Modulation of murine macrophage function by IL-13. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
    Show all 3 references for 1305069

More Proteins for IL-13 Interaction Partners

Human Interleukin 13 (IL13) interaction partners

  1. These observations suggest that mechanical stretch may induce an influx of Ca(2 (show CA2 Proteins)+) and up-regulation of IL-13 and MMP-9 (show MMP9 Proteins) expression in 16HBE cells via activation of TRPC1 (show TRPC1 Proteins)

  2. Studies show that bronchoalveolar lavage fluid (BALF) soluble triggering receptor expressed on myeloid cells-1 (show TREM1 Proteins) (sTREM-1) levels do not discriminate between mild-to-moderate asthma and chronic obstructive pulmonary disease (COPD (show ARCN1 Proteins)), in contrast, the interleukin 6 (IL-6 (show IL6 Proteins))/interleukine 13 (IL-13) ratio measured in BALF effectively differentiated these two diseases.

  3. The presented data substantiate the hypothesis that claudin-18 (show CLDN18 Proteins) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (show CLDN18 Proteins). These data also suggest that the loss of claudin-18 (show CLDN18 Proteins) is associated with increased sensitization to aeroantigens and airway responsiveness

  4. IL-12 pretreatment increased TCR-induced IFN-gamma, TNF-alpha, IL-13, IL-4 and IL-10 production. This suggests that prior exposure to IL-12 potentiates the TCR-induced release of a range of cytokines

  5. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Proteins) and IL-13, down-regulates matriptase (show ST14 Proteins) as well as prostasin (show PRSS8 Proteins) through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Proteins)

  6. investigated the role of six potentially functional variants of the IL4 (show IL4 Proteins), IL13, and IL4R (show IL4R Proteins) genes in gastrointestinal cancer; both IL13 rs20541 and rs1800925 were not associated with gastrointestinal cancer risk for any of the genetic models and subgroup analyses [meta-analysis]

  7. IL13 in bronchial epithelial cells and bronchial alveolar lavage fluid, rather than RAD50 (show RAD50 Proteins), IL4 (show IL4 Proteins), or IL5 (show IL5 Proteins), is more likely to be the asthma susceptibility gene.

  8. We also found that the activation of H4R (show HRH4 Proteins) caused the release of IL-13 and RANTES (show CCL5 Proteins) on human mast cells.these data demonstrate that the H4R (show HRH4 Proteins) activates divergent signaling pathways to induce cytokine and chemokine (show CCL1 Proteins) production in human mast cells

  9. IL13 Arg130Gln genotypes can play a role in genetic susceptibility to allergy via regulation of serum total IgE levels and affecting IFN-gamma (show IFNG Proteins) gene expression.

  10. The GG genotype of IL-13 130A/G cytokine gene might be involved in the induced production of total IgE and IL-13 cytokine serum levels suggesting IL-13 may be important in the signalling of asthma.

Mouse (Murine) Interleukin 13 (IL13) interaction partners

  1. findings suggest that a leukotriene B4 receptor-2-linked cascade plays a pivotal role in LPS/TLR4 (show TLR4 Proteins) signaling for IL-13 synthesis in mast cells, thereby potentially exacerbating allergic response.

  2. Study found IL-13 to be critically involved in the development of chemical-induced asthma, as shown by using IL-13 KO mice, and more specifically in the effector phase as confirmed by anti- IL-13 antibody treatment.

  3. these studies show that fibrosis, steatosis, cholestasis, and ductular reaction are simultaneously controlled but distinctly regulated by interleukin-13 signaling

  4. Our data support that impaired clearance of inhaled allergens triggering IL-13 production by multiple cell types in the airways plays an important role in the pathogenesis of type 2 airway inflammation and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for children with allergen-induced asthma.

  5. this study shows that wild-type mice develop an eosinophilic Th2 airway disease in response to Alternaria alternata exposure, whereas IL-13-deficient mice exhibit a primarily neutrophilic response

  6. this study shows that IL-17A (show IL17A Proteins) contributes to asthma pathophysiology by increasing the capacity of IL-13 to activate intracellular signaling pathways, such as STAT6 (show STAT6 Proteins) activation

  7. RCM-1 (show TNNI3 Proteins) reduced IL-13 and STAT6 (signal transducer and activator of transcription 6 (show STAT6 Proteins)) signaling and prevented the expression of the STAT6 (show STAT6 Proteins) target genes Spdef and Foxa3 (show FOXA3 Proteins), which are key transcriptional regulators of goblet cell differentiation.

  8. IL-13 suppressed both the activation-induced apoptosis of CD4 (show CD4 Proteins)(+) T cells and the expression of p53 (show TP53 Proteins) and FasL (show FASL Proteins).

  9. We clearly show that miR (show MLXIP Proteins)-155 has a previously unknown direct regulatory role in the ILC2 subset that affects IL-33 (show IL33 Proteins) receptor expression, IL-33 (show IL33 Proteins) responsiveness, and IL-13 production as well as proliferation capability, possibly due to defects in GATA-3 (show GATA3 Proteins) function.

  10. The presented data substantiate the hypothesis that claudin-18 (show CLDN18 Proteins) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (show CLDN18 Proteins). These data also suggest that the loss of claudin-18 (show CLDN18 Proteins) is associated with increased sensitization to aeroantigens and airway responsiveness

Cow (Bovine) Interleukin 13 (IL13) interaction partners

  1. T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Proteins) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.

IL-13 (IL13) Protein Profile

Protein Summary

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Alternative names and synonyms associated with IL-13 (IL13)

  • interleukin 13 (IL13)
  • interleukin 13 (Il13)
  • interleukin-13 (IL-13)
  • Il-13 protein
  • IL13 protein
  • L13 protein
  • P600 protein

Protein level used designations for Interleukin 13 Proteins (IL13)

interleukin 13 , interleukin-13 , T-cell activation protein P600 , IL-13

100137221 Papio anubis
3596 Homo sapiens
16163 Mus musculus
100720118 Cavia porcellus
116553 Rattus norvegicus
396721 Sus scrofa
281247 Bos taurus
442990 Canis lupus familiaris
574325 Macaca mulatta
664707 Ovis aries
474361 Gallus gallus
449564 Pan troglodytes
100034113 Equus caballus
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