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IL-13 Protein (His-Avi Tag,Biotin)

IL13 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Catalog No. ABIN7274901
  • Target See all IL-13 (IL13) Proteins
    IL-13 (IL13) (Interleukin 13 (IL13))
    Protein Type
    Recombinant
    Origin
    • 24
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 28
    • 15
    • 8
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-13 protein is labelled with His-Avi Tag,Biotin.
    Sequence
    Gly21-Asn132
    Purity
    > 95% as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Biotinylated Human IL-13, His Tag at 2μg/ml (100μl/well) on the streptavidin (5μg/ml) precoated plate. Dose response curve for Human IL-13Ra2, hFc Tag with the EC50 of 1.4μg/ml determined by ELISA. See testing image for detail.
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    Discover our top product IL13 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Alternative Name
    IL-13 (IL13 Products)
    Synonyms
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Background
    IL13, IL-13, interleukin 13, NC30, P600, ALRH, BHR1, MGC116786, MGC116788, MGC116789,Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
    Molecular Weight
    15.3 kDa. Due to glycosylation, the protein migrates to 15 kDa and 35-45 kDa based on Tris-Bis PAGE result.
    Pathways
    JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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