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Browse our anti-SOCS3 (SOCS3) Antibodies

Full name:
anti-Suppressor of Cytokine Signaling 3 Antibodies (SOCS3)
On are 220 Suppressor of Cytokine Signaling 3 (SOCS3) Antibodies from 29 different suppliers available. Additionally we are shipping SOCS3 Kits (50) and SOCS3 Proteins (19) and many more products for this protein. A total of 297 SOCS3 products are currently listed.
ATOD4, Cis3, Cish3, EF-10, Ef10, fj09e12, MGC64393, MGC75749, MGC81248, Socs-3, SOCS3, Ssi-3, Ssi3, wu:fj09e12, xsocs3, zgc:56537
list all antibodies Gene Name GeneID UniProt
SOCS3 9021 O14543
SOCS3 12702 O35718
SOCS3 89829 O88583

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Top referenced anti-SOCS3 Antibodies

  1. Human Polyclonal SOCS3 Primary Antibody for WB - ABIN493472 : Alexander, Hilton: The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. in Annual review of immunology 2004 (PubMed)
    Show all 5 references for ABIN493472

  2. Human Polyclonal SOCS3 Primary Antibody for IF (p), IHC (p) - ABIN670416 : Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for ABIN670416

  3. Human Monoclonal SOCS3 Primary Antibody for WB - ABIN94467 : Neuwirt, Puhr, Cavarretta, Mitterberger, Hobisch, Culig: Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion. in Endocrine-related cancer 2007 (PubMed)
    Show all 4 references for ABIN94467

  4. Human Monoclonal SOCS3 Primary Antibody for WB - ABIN153119 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

  5. Human Polyclonal SOCS3 Primary Antibody for IHC, ELISA - ABIN1585262 : van de Loo, Veenbergen, van den Brand, Bennink, Blaney-Davidson, Arntz, van Beuningen, van der Kraan, van den Berg: Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function. in Arthritis and rheumatism 2012 (PubMed)

  6. Human Polyclonal SOCS3 Primary Antibody for ELISA, WB - ABIN184566 : Roberts, Robb, Rakar, Hartley, Cluse, Nicola, Metcalf, Hilton, Alexander: Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)

More Antibodies against SOCS3 Interaction Partners

Zebrafish Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. we report the surprising finding that zebrafish respond to optic nerve lesion by inducing the expression of Sfpq (show SFPQ Antibodies) and Socs3a

  2. stat3 (show STAT3 Antibodies)/socs3 pathway is a key response in all tissue regeneration in zebrafish.

  3. Trpm7 (show TRPM7 Antibodies) regulates exocrine pancreatic development via the Mg(2 (show MCOLN1 Antibodies)+)-sensitive Socs3a pathway.

  4. SOCS3 expression in response to trauma is unaffected by blockade of the mitogen-activated protein kinase (show MAPK1 Antibodies) pathway by chemical inhibitors

  5. The suppressor of cytokine signaling 3 gene was identified in this species, and the base sequence and deduced amino acid sequence are presented.

  6. in homozygotes, GH signaling is reduced by the action of the SOCS1 (show SOCS1 Antibodies) and SOCS3 proteins.

Human Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. Treatment of isolinderalactone increased the protein level of SCOS3, decreased phosphorylation of the STAT3 (show STAT3 Antibodies) and suppressed expression of the down-stream genes of the X-linked inhibitor of apoptosis protein (show XIAP Antibodies)

  2. miR (show MLXIP Antibodies)-203 and miR (show MLXIP Antibodies)-221 regulate SOCS1 (show SOCS1 Antibodies) and SOCS3 in essential thrombocythemia

  3. Dysregulation of SOCS3 functions can cause a variety of diseases, including allergy, autoimmune diseases, inflammation and cancer. (Review)

  4. induction of SOCS3 may be a novel mechanism by which FXR (show NR1H4 Antibodies) exerts its anti-hepatocellular carcinoma effects

  5. H. pylori infection induced hepatic insulin (show INS Antibodies) resistance by the c-Jun (show JUN Antibodies)/miR (show MLXIP Antibodies)-203/SOCS3 signaling pathway and provide possible implications with regard to resolving insulin (show INS Antibodies) resistance.

  6. A significant relevance involved in SOCS3 gene polymorphisms and infantile asthma development based on a Chinese Han population.

  7. In hepatocellular carcinoma tumor tissues, SOCS3 showed an increased methylation frequency and intensity compared with that in the adjacent non-tumor tissues.

  8. Data suggest that PCSK9 (show PCSK9 Antibodies) is involved in regulation of lipid metabolism in hepatocytes by proinflammatory cytokine TNFalpha (show TNF Antibodies); induction of lipogenesis and insulin (show INS Antibodies) resistance in liver (as seen in obesity) involves up-regulation of both PCSK9 (show PCSK9 Antibodies) and SOCS3.

  9. Epigenetic inhibition of SOCS3 is regulated by miR1264 which specifically targets DNMT1 (show DNMT1 Antibodies) transcript.

  10. Decreased SOCS3 expression is associated with cholangiocarcinoma.

Pig (Porcine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. SOCS3 is an important negative regulator of insulin (show INS Antibodies) signaling in porcine adipocytes.

Cow (Bovine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. Low SOCS3 expression is required for milk synthesis and proliferation of dairy cow mammary epithelial cells in vitro.

  2. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 (show IL10 Antibodies) and SOCS-3, which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Mouse (Murine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. CCR5 (show CCR5 Antibodies) blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Antibodies)-Stat3 (show STAT3 Antibodies) signaling pathway via upregulation of SOCS3.

  2. AHR (show AHR Antibodies) plays protective roles against high-fat diet-induced hepatic steatosis and the subsequent lipotoxicity via direct transcriptional regulation of Socs3 gene expression.

  3. The liver regenerative effects of HCM appear to be mediated by persistent and uninhibited expression of STAT3 (show STAT3 Antibodies) in the liver, which results from decreased expression of SOCS3

  4. SOCS3 gene expression attenuates contact hypersensitivity by suppressing MMP12 (show MMP12 Antibodies) production.

  5. These results suggest that neuronal and glial cell SOCS3 limits pathological retinal angiogenesis by suppressing VEGF signaling.

  6. Socs3 deletion in cortical neurons promotes sprouting of corticospinal axons after unilateral pyramidotomy, restoring skilled locomotion.

  7. SOCS3-deficient and sufficient B-lineage cell migration towards CXCL12 (show CXCL12 Antibodies) in vitro was undistinguishable, and B-lineage cell amoeboid motility within BM parenchyma was also unaffected by SOCS3-deficiency

  8. RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation

  9. findings suggest that SOCS3 may represent a key factor that exacerbates the development of myocardial IRI.

  10. The critical function of SOCS3 is as a negative regulator of MDSC development and function via inhibition of STAT3 (show STAT3 Antibodies) activation.

SOCS3 Antigen Profile

Antigen Summary

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Alternative names and synonyms associated with SOCS3

  • suppressor of cytokine signaling 3a (socs3a) antibody
  • suppressor of cytokine signaling 3 (socs3) antibody
  • suppressor of cytokine signaling 3 (SOCS3) antibody
  • suppressor of cytokine signaling 3a (socs3) antibody
  • suppressor of cytokine signaling 3 (LOC100227853) antibody
  • suppressor of cytokine signaling 3 (Socs3) antibody
  • ATOD4 antibody
  • Cis3 antibody
  • Cish3 antibody
  • EF-10 antibody
  • Ef10 antibody
  • fj09e12 antibody
  • MGC64393 antibody
  • MGC75749 antibody
  • MGC81248 antibody
  • Socs-3 antibody
  • SOCS3 antibody
  • Ssi-3 antibody
  • Ssi3 antibody
  • wu:fj09e12 antibody
  • xsocs3 antibody
  • zgc:56537 antibody

Protein level used designations for SOCS3

suppressor of cytokine signaling 3 , suppressor of cytokine signaling 3a , STAT-induced STAT inhibitor 3 , cytokine-inducible SH2 protein 3 , cytokine signaling suppressor , SOCS-3 , CIS-3 , E2a-Pbx1 target gene in fibroblasts 10 , cytokine inducible SH2-containing protein 3 , suppressors of cytokine signaling 3

335409 Danio rerio
380467 Xenopus laevis
394588 Xenopus (Silurana) tropicalis
414533 Xenopus laevis
448204 Xenopus (Silurana) tropicalis
454921 Pan troglodytes
100050730 Equus caballus
100192332 Gasterosteus aculeatus
100272212 Oncorhynchus mykiss
100294595 Ovis aries
100528984 Ictalurus punctatus
100227853 Taeniopygia guttata
9021 Homo sapiens
442949 Canis lupus familiaris
493186 Sus scrofa
282081 Bos taurus
12702 Mus musculus
89829 Rattus norvegicus
395299 Gallus gallus
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