Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human SOCS3 Antibodies:
anti-Mouse (Murine) SOCS3 Antibodies:
anti-Rat (Rattus) SOCS3 Antibodies:
Go to our pre-filtered search.
Human Polyclonal SOCS3 Primary Antibody for WB - ABIN493472
Alexander, Hilton: The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. in Annual review of immunology 2004
Show all 5 references for ABIN493472
Human Polyclonal SOCS3 Primary Antibody for IF (p), IHC (p) - ABIN670416
Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. in Biochemical and biophysical research communications 2010
Show all 4 references for ABIN670416
Human Monoclonal SOCS3 Primary Antibody for WB - ABIN94467
Neuwirt, Puhr, Cavarretta, Mitterberger, Hobisch, Culig: Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion. in Endocrine-related cancer 2007
Show all 4 references for ABIN94467
Human Polyclonal SOCS3 Primary Antibody for IHC, ELISA - ABIN1585262
van de Loo, Veenbergen, van den Brand, Bennink, Blaney-Davidson, Arntz, van Beuningen, van der Kraan, van den Berg: Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function. in Arthritis and rheumatism 2012
Cow (Bovine) Polyclonal SOCS3 Primary Antibody for WB - ABIN374066
Roberts, Robb, Rakar, Hartley, Cluse, Nicola, Metcalf, Hilton, Alexander: Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. in Proceedings of the National Academy of Sciences of the United States of America 2001
we report the surprising finding that zebrafish respond to optic nerve lesion by inducing the expression of Sfpq (show SFPQ Antibodies) and Socs3a
stat3 (show STAT3 Antibodies)/socs3 pathway is a key response in all tissue regeneration in zebrafish.
Trpm7 (show TRPM7 Antibodies) regulates exocrine pancreatic development via the Mg(2 (show MCOLN1 Antibodies)+)-sensitive Socs3a pathway.
SOCS3 expression in response to trauma is unaffected by blockade of the mitogen-activated protein kinase (show MAPK1 Antibodies) pathway by chemical inhibitors
The suppressor of cytokine signaling 3 gene was identified in this species, and the base sequence and deduced amino acid sequence are presented.
in homozygotes, GH signaling is reduced by the action of the SOCS1 (show SOCS1 Antibodies) and SOCS3 proteins.
Dysregulation of SOCS3 functions can cause a variety of diseases, including allergy, autoimmune diseases, inflammation and cancer. (Review)
induction of SOCS3 may be a novel mechanism by which FXR (show NR1H4 Antibodies) exerts its anti-hepatocellular carcinoma effects
H. pylori infection induced hepatic insulin (show INS Antibodies) resistance by the c-Jun (show JUN Antibodies)/miR (show MLXIP Antibodies)-203/SOCS3 signaling pathway and provide possible implications with regard to resolving insulin (show INS Antibodies) resistance.
A significant relevance involved in SOCS3 gene polymorphisms and infantile asthma development based on a Chinese Han population.
In hepatocellular carcinoma tumor tissues, SOCS3 showed an increased methylation frequency and intensity compared with that in the adjacent non-tumor tissues.
Data suggest that PCSK9 (show PCSK9 Antibodies) is involved in regulation of lipid metabolism in hepatocytes by proinflammatory cytokine TNFalpha (show TNF Antibodies); induction of lipogenesis and insulin (show INS Antibodies) resistance in liver (as seen in obesity) involves up-regulation of both PCSK9 (show PCSK9 Antibodies) and SOCS3.
Epigenetic inhibition of SOCS3 is regulated by miR1264 which specifically targets DNMT1 (show DNMT1 Antibodies) transcript.
Decreased SOCS3 expression is associated with cholangiocarcinoma.
SOCS3 down-expression induces lineage commitment towards erythroid progenitor cell fate by activation of erythroid-specific gene in HSCs
Suggest racial/ethnic- and/or sex-specific association between the SOCS3 A+930-->G (rs4969168) SNP and serum APOA1 (show APOA1 Antibodies)/LDL cholesterol levels in some Chinese populations.
SOCS3 is an important negative regulator of insulin (show INS Antibodies) signaling in porcine adipocytes.
Low SOCS3 expression is required for milk synthesis and proliferation of dairy cow mammary epithelial cells in vitro.
Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 (show IL10 Antibodies) and SOCS-3, which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.
CCR5 (show CCR5 Antibodies) blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Antibodies)-Stat3 (show STAT3 Antibodies) signaling pathway via upregulation of SOCS3.
AHR (show AHR Antibodies) plays protective roles against high-fat diet-induced hepatic steatosis and the subsequent lipotoxicity via direct transcriptional regulation of Socs3 gene expression.
The liver regenerative effects of HCM appear to be mediated by persistent and uninhibited expression of STAT3 (show STAT3 Antibodies) in the liver, which results from decreased expression of SOCS3
SOCS3 gene expression attenuates contact hypersensitivity by suppressing MMP12 (show MMP12 Antibodies) production.
These results suggest that neuronal and glial cell SOCS3 limits pathological retinal angiogenesis by suppressing VEGF signaling.
Socs3 deletion in cortical neurons promotes sprouting of corticospinal axons after unilateral pyramidotomy, restoring skilled locomotion.
SOCS3-deficient and sufficient B-lineage cell migration towards CXCL12 (show CXCL12 Antibodies) in vitro was undistinguishable, and B-lineage cell amoeboid motility within BM parenchyma was also unaffected by SOCS3-deficiency
RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation
findings suggest that SOCS3 may represent a key factor that exacerbates the development of myocardial IRI.
The critical function of SOCS3 is as a negative regulator of MDSC development and function via inhibition of STAT3 (show STAT3 Antibodies) activation.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
suppressor of cytokine signaling 3
, suppressor of cytokine signaling 3a
, STAT-induced STAT inhibitor 3
, cytokine-inducible SH2 protein 3
, cytokine signaling suppressor
, E2a-Pbx1 target gene in fibroblasts 10
, cytokine inducible SH2-containing protein 3
, suppressors of cytokine signaling 3