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Browse our anti-SOCS3 (SOCS3) Antibodies

Full name:
anti-Suppressor of Cytokine Signaling 3 Antibodies (SOCS3)
On are 219 Suppressor of Cytokine Signaling 3 (SOCS3) Antibodies from 28 different suppliers available. Additionally we are shipping SOCS3 Kits (48) and SOCS3 Proteins (24) and many more products for this protein. A total of 298 SOCS3 products are currently listed.
ATOD4, Cis3, Cish3, EF-10, Ef10, fj09e12, MGC64393, MGC75749, MGC81248, Socs-3, SOCS3, Ssi-3, Ssi3, wu:fj09e12, xsocs3, zgc:56537
list all antibodies Gene Name GeneID UniProt
SOCS3 9021 O14543
SOCS3 12702 O35718
SOCS3 89829 O88583

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Top referenced anti-SOCS3 Antibodies

  1. Human Polyclonal SOCS3 Primary Antibody for WB - ABIN493472 : Alexander, Hilton: The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. in Annual review of immunology 2004 (PubMed)
    Show all 5 references for ABIN493472

  2. Human Polyclonal SOCS3 Primary Antibody for ELISA, FACS - ABIN670416 : Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for ABIN670416

  3. Human Polyclonal SOCS3 Primary Antibody for IHC, IHC (p) - ABIN4355049 : Harris, Apolzan: Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. in Physiology & behavior 2014 (PubMed)
    Show all 2 references for ABIN4355049

  4. Human Polyclonal SOCS3 Primary Antibody for IHC, ELISA - ABIN1585262 : van de Loo, Veenbergen, van den Brand, Bennink, Blaney-Davidson, Arntz, van Beuningen, van der Kraan, van den Berg: Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function. in Arthritis and rheumatism 2012 (PubMed)

  5. Human Monoclonal SOCS3 Primary Antibody for WB - ABIN153119 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

  6. Cow (Bovine) Polyclonal SOCS3 Primary Antibody for WB - ABIN374066 : Roberts, Robb, Rakar, Hartley, Cluse, Nicola, Metcalf, Hilton, Alexander: Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)

More Antibodies against SOCS3 Interaction Partners

Zebrafish Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. we report the surprising finding that zebrafish respond to optic nerve lesion by inducing the expression of Sfpq (show SFPQ Antibodies) and Socs3a

  2. stat3 (show STAT3 Antibodies)/socs3 pathway is a key response in all tissue regeneration in zebrafish.

  3. Trpm7 (show TRPM7 Antibodies) regulates exocrine pancreatic development via the Mg(2 (show MCOLN1 Antibodies)+)-sensitive Socs3a pathway.

  4. SOCS3 expression in response to trauma is unaffected by blockade of the mitogen-activated protein kinase (show MAPK1 Antibodies) pathway by chemical inhibitors

  5. The suppressor of cytokine signaling 3 gene was identified in this species, and the base sequence and deduced amino acid sequence are presented.

  6. in homozygotes, GH signaling is reduced by the action of the SOCS1 (show SOCS1 Antibodies) and SOCS3 proteins.

Human Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. SHP2 (show PTPN11 Antibodies), SOCS3 and PIAS3 (show PIAS3 Antibodies) levels are reduced in medulloblastomas in vivo and in vitro, of which PIAS3 (show PIAS3 Antibodies) downregulation is more reversely correlated with STAT3 (show STAT3 Antibodies) activation. In resveratrol-suppressed medulloblastoma cells with STAT3 (show STAT3 Antibodies) downregulation and decreased incidence of STAT3 (show STAT3 Antibodies) nuclear translocation, PIAS3 (show PIAS3 Antibodies) is upregulated, the SHP2 (show PTPN11 Antibodies) level remains unchanged and SOCS3 is downregulated.

  2. SOCS3 methylation status was associated with multiple metabolic syndrome traits, including central obesity, fat depots, insulin (show INS Antibodies) responsiveness, and plasma lipids.

  3. The results revealed that although the expression levels of SOCS1 (show SOCS1 Antibodies), SOCS3 and, in particular, pSHP2, tend to decrease in the four types of astrocytomas, PIAS3 (show PIAS3 Antibodies) downregulation is more negatively correlated with STAT3 (show STAT3 Antibodies) activation in the stepwise progress of astrocytomas and would indicate an unfavorable outcome.

  4. reduced type I interferon (show IFNA Antibodies) production in obesity is caused by SOCS3 overexpression as well as tolerance induced by leptin (show LEP Antibodies)

  5. Data suggest that single nucleotide polymorphisms (SNPs) in suppressor of cytokine signaling 3 (SOCS3) may play a role in the pathogenesis of metabolic syndrome (MS).

  6. that siRNA-mediated SOCS3 knock-down in human osteoarthritic chondrocytes increased production of IL-1beta (show IL1B Antibodies)-induced prostaglandin E2

  7. SOCS3 promoter was methylated in H2228 cells as well as in three cases of seven EML4 (show EML4 Antibodies)-ALK (show ALK Antibodies)-positive lung cancer tissues.

  8. Data suggest that microRNA miR19a3p plays an important role in beta cell function, and that the miR (show MLXIP Antibodies)-19a-3p/suppressor of cytokine signaling 3 (SOCS3) axis may become a potential therapeutic target for diabetes.

  9. Significantly higher levels of suppressor of cytokine signalling (show SOCS1 Antibodies) proteins SOCS3 and SOCS4 (show SOCS6 Antibodies) in non-healing chronic wounds compared to the healing/healed chronic wounds were observed at the transcript level.

  10. The rs115785973 could be regulated by miR (show MLXIP Antibodies)-4308 which caused an up-regulation ofsuppressor of cytokine signaling 3 in patients with GA and AA genotype.

Pig (Porcine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. SOCS3 is an important negative regulator of insulin (show INS Antibodies) signaling in porcine adipocytes.

Cow (Bovine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. Low SOCS3 expression is required for milk synthesis and proliferation of dairy cow mammary epithelial cells in vitro.

  2. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 (show IL10 Antibodies) and SOCS-3, which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Mouse (Murine) Suppressor of Cytokine Signaling 3 (SOCS3) interaction partners

  1. These results indicate that Platelet-activating Factor -mediated endotoxin tolerance is initiated via IDO (show IDO1 Antibodies)- and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies)-dependent expression of SOCS3.

  2. expression in leptin receptor-positive cells contributes to fasting-induced hyperphagia and weight regain

  3. a novel negative feedback loop mediated by STAT3 (show STAT3 Antibodies)-SOCS3, which is tightly controlled by SENP1 (show SENP1 Antibodies) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Antibodies)), in IFN-gamma (show IFNG Antibodies) signaling, is reported.

  4. Vasoproliferative retinopathies may benefit from a CNTF (show CNTF Antibodies)-dependent and SOCS3-mediated angiomodulatory effect.

  5. this study shows that fungal pattern receptors share with other ITAM-coupled receptors the capacity to produce cross-inhibition through a mechanism involving STAT3 (show STAT3 Antibodies) and induction of SOCS3 and IL-10 (show IL10 Antibodies), but that cannot be explained through type I IFN signaling

  6. this study shows that suppression of IL-6 (show IL6 Antibodies)/Stat3 (show STAT3 Antibodies) pathway in dendritic cells by paeoniflorin is mediated via upregulation of Socs3

  7. Study indicated that SOCS3 suppresses complete polarization to M1 phenotype through blocking IL6 (show IL6 Antibodies) production, and Abeta (show APP Antibodies)-challenged primary-cultured microglia replicate the in vivo gene expression pattern of microglia in APPswe/PS1dE9 mice

  8. Results identify unrecognized functions of Yes-associated protein (YAP (show YAP1 Antibodies)) in preventing reactive astrogliosis and reveal a pathway of YAP (show YAP1 Antibodies)- suppressor of cytokine signaling 3 (SOCS (show CISH Antibodies)) for the negatively control of neuroinflammation.

  9. SOCS3 serves as an immune modulator interfering with T cells and B cells, and SOCS3 may act as a predictive marker for immune modulation of mesenchymal stromal cells.

  10. Signal transducer and activator of transcription 3 (show STAT3 Antibodies) and suppressor of cytokine signaling 3 play important, yet unexpected, roles in NG2 (show Vcan Antibodies) cell proliferation and differentiation after spinal cord injury.

SOCS3 Antigen Profile

Antigen Summary

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Alternative names and synonyms associated with SOCS3

  • suppressor of cytokine signaling 3a (socs3a) antibody
  • suppressor of cytokine signaling 3 (socs3) antibody
  • suppressor of cytokine signaling 3 (SOCS3) antibody
  • suppressor of cytokine signaling 3a (socs3) antibody
  • suppressor of cytokine signaling 3 (LOC100227853) antibody
  • suppressor of cytokine signaling 3 (Socs3) antibody
  • ATOD4 antibody
  • Cis3 antibody
  • Cish3 antibody
  • EF-10 antibody
  • Ef10 antibody
  • fj09e12 antibody
  • MGC64393 antibody
  • MGC75749 antibody
  • MGC81248 antibody
  • Socs-3 antibody
  • SOCS3 antibody
  • Ssi-3 antibody
  • Ssi3 antibody
  • wu:fj09e12 antibody
  • xsocs3 antibody
  • zgc:56537 antibody

Protein level used designations for SOCS3

suppressor of cytokine signaling 3 , suppressor of cytokine signaling 3a , STAT-induced STAT inhibitor 3 , cytokine-inducible SH2 protein 3 , cytokine signaling suppressor , SOCS-3 , CIS-3 , E2a-Pbx1 target gene in fibroblasts 10 , cytokine inducible SH2-containing protein 3 , suppressors of cytokine signaling 3

335409 Danio rerio
380467 Xenopus laevis
394588 Xenopus (Silurana) tropicalis
414533 Xenopus laevis
448204 Xenopus (Silurana) tropicalis
454921 Pan troglodytes
100050730 Equus caballus
100192332 Gasterosteus aculeatus
100272212 Oncorhynchus mykiss
100294595 Ovis aries
100528984 Ictalurus punctatus
100227853 Taeniopygia guttata
9021 Homo sapiens
442949 Canis lupus familiaris
493186 Sus scrofa
282081 Bos taurus
12702 Mus musculus
89829 Rattus norvegicus
395299 Gallus gallus
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