EDG-4
LPAR2
PC
Whole Cell Lysate
Catalog No. ABIN924991
$553.85
Plus shipping costs $50.00
100 μL
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for EDG-4 (ABIN924991)
Target
EDG4 (LPAR2)
(Lysophosphatidic Acid Receptor 2 (LPAR2))
Application
Positive Control (PC)
Lysate Fraction
Whole Cell Lysate
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Application Notes
- For use as a positive control with EDG-4 monoclonal antibodies catalog numbers MC-914 and MC-915. Use 10-20 µl of EDG-4 cell lysate per lane as a control for using EDG-4 antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Cell lysate provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol.
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Storage
- -20 °C
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- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
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Alternative Name
- EDG-4
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Background
- EDG-4 Transfected Cell Positive Control Lysate. EDG-4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-4 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
Target
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