Lysophosphatidic Acid Receptor 2 (EDG-4) Lysate
LPAR2
WB
Whole Cell Lysate
Catalog No. ABIN2764008
$176.00
Plus shipping costs $50.00
100 μL
Shipping to:
United States
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Quick Overview for Lysophosphatidic Acid Receptor 2 (EDG-4) Lysate (ABIN2764008)
Target
EDG4 (LPAR2)
(Lysophosphatidic Acid Receptor 2 (LPAR2))
Application
Western Blotting (WB)
Lysate Fraction
Whole Cell Lysate
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Characteristics
- EDG4 (LPA2) Transfected Cell Positive Control Lysate,EDG4 (LPA2) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
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Application Notes
- For use as a positive control with EDG4 (NT) monoclonal antibody for Western blot analysis. Will not work with EDG4 (CT) antibody. Grown in RH7 cells.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Provided in 10 % glycerol, 0.063 M Tris-HCl ( pH 6.8), 2 % SDS and 0.002 % bromophenol blue, 5 % 2-mercaptoethanol
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
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Alternative Name
- Lysophosphatidic Acid Receptor 2 (EDG-4)
Target
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