Browse our anti-MAP2K7 (MAP2K7) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 7 Antibodies (MAP2K7)
On are 147 Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibodies from 23 different suppliers available. Additionally we are shipping MAP2K7 Kits (15) and MAP2K7 Proteins (13) and many more products for this protein. A total of 186 MAP2K7 products are currently listed.
2, 5930412N11Rik, JNKK, JNKK 2, Jnkk2, MAP2K7, map2k7-A, MAPKK7, MAPKK 7, Mek7, MEK 7, MKK7, Prkmk7, SAPKK-4, SAPKK4, sek2, si:ch211-254d18.2
list all antibodies Gene Name GeneID UniProt
MAP2K7 363855 Q4KSH7
MAP2K7 5609 O14733
MAP2K7 26400 Q8CE90

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Most Popular Reactivities for anti-MAP2K7 (MAP2K7) Antibodies

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anti-Rat (Rattus) MAP2K7 Antibodies:

anti-Human MAP2K7 Antibodies:

anti-Mouse (Murine) MAP2K7 Antibodies:

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Top referenced anti-MAP2K7 Antibodies

  1. Human Monoclonal MAP2K7 Primary Antibody for ICC, FACS - ABIN969271 : Yoshizawa, Hammaker, Sweeney, Boyle, Firestein: Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for 969271

  2. Cow (Bovine) Polyclonal MAP2K7 Primary Antibody for WB - ABIN2783609 : Tornatore, Marasco, Dathan, Vitale, Benedetti, Papa, Franzoso, Ruvo, Monti: Gadd45 beta forms a homodimeric complex that binds tightly to MKK7. in Journal of molecular biology 2008 (PubMed)

  3. Human Polyclonal MAP2K7 Primary Antibody for ELISA, WB - ABIN1533091 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

More Antibodies against MAP2K7 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) interaction partners

  1. MEK (show MAP2K1 Antibodies) activation cooperates with Cdkn2a (show CDKN2A Antibodies) and Pten (show PTEN Antibodies) inactivation to induce melanoma

  2. MKK7 undergoes neddylation in human breast cancer cells

  3. In an Eastern Chinese population, carriers of MAP2K7 rs3679T variant genotypes had an increased risk of NSCLC.

  4. Therefore, EGF (show EGF Antibodies) is suggested to induce E-cadherin (show CDH1 Antibodies) down-regulation at the transcriptional level through the MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) pathway, which might result in, at least in part, the induction of cellular morphological changes and cell migration in LoVo cells.

  5. combined pan-RAF and MEK inhibition can overcome intrinsic and acquired resistance to single-agent RAF/MEK inhibition, supporting dual pan-RAF and MEK inhibition as a novel therapeutic strategy for BRAF- and KRAS-mutant cancers

  6. our study suggested that black rice anthocyanins extract suppress metastasis in breast cancer cells by targeting the RAS/RAF (show RAF1 Antibodies)/MAPK (show MAPK1 Antibodies) pathway

  7. Crystal structures of the wild type and C218S mutant of MAP2K7 were determined. Cys218 plays a crucial role in configuring an auto-inhibition form of MAP2K7.

  8. We found that the MKK7 p.Glu116Lys rare polymorphism was significantly associated with lung cancer risk, progression and prognosis

  9. we explored the effects of selumetinib in combination with gefitinib in a panel of TNBC cells, in order to evaluate whether the simultaneous blockade of the EGFR (show EGFR Antibodies) and the RAS/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) pathway might increase the antitumor activity of selumetinib in TNBC.

  10. a widespread role for the JNK (show MAPK8 Antibodies)-CELF2 (show CELF2 Antibodies) axis in controlling splicing during T-cell activation, including a specific role in propagating JNK (show MAPK8 Antibodies) signaling.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) interaction partners

  1. The loss of mkk4 (show MAP2K4 Antibodies) and mkk7 locks damaged exocrine cells in a permanently de-differentiated state.

  2. Arrestin-3 (show ARRB2 Antibodies) directly interacts with MKK7 and promotes JNK3alpha2 phosphorylation by both MKK4 (show MAP2K4 Antibodies) and MKK7 in vitro as well as in intact cells.

  3. MKK7 is specifically phosphorylated in the neurite shaft which triggers Map1b (show MAP1B Antibodies) phosphorylation to regulate microtubule bundling leading to neurite elongation.

  4. Data indicate that mitogen activated protein kinase kinase 7 (MKK7) plays a critical regulatory role in the c-Jun N-terminal kinase pathway in a murine model of rheumatoid arthritis.

  5. a novel function for the stress kinase MKK7 as a regulator of the circadian clock in mammalian cells at steady state.

  6. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.

  7. MKK4 (show MAP2K4 Antibodies)/7 and JNK1 (show MAPK8 Antibodies)/2 played regulatory role in cytoskeleton reorganization during vaccinia virus infection.

  8. This study demonistrated that Stress-activated protein kinase (show CDK7 Antibodies) MKK7 regulates axon elongation in the developing cerebral cortex.

  9. The results reveal an essential role of MKK7 in cardiomyocytes for protecting the heart from hypertrophic insults thereby preventing the transition to heart failure.

  10. The role of NF-kappaB (show NFKB1 Antibodies) and c-jun N-terminal kinase (JNK) activation in RANKL (show TNFSF11 Antibodies)-induced osteoclast differentiation was investigated using an adenovirus vector carrying the dominant negative 1kappaB kinase 2 gene or dominant negative MKK7 gene.

MAP2K7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Alternative names and synonyms associated with MAP2K7

  • mitogen-activated protein kinase kinase 7 (MAP2K7) antibody
  • mitogen activated protein kinase kinase 7 (Map2k7) antibody
  • mitogen-activated protein kinase kinase 7 (Map2k7) antibody
  • mitogen-activated protein kinase kinase 7 (map2k7) antibody
  • 2 antibody
  • 5930412N11Rik antibody
  • JNKK antibody
  • JNKK 2 antibody
  • Jnkk2 antibody
  • MAP2K7 antibody
  • map2k7-A antibody
  • MAPKK7 antibody
  • MAPKK 7 antibody
  • Mek7 antibody
  • MEK 7 antibody
  • MKK7 antibody
  • Prkmk7 antibody
  • SAPKK-4 antibody
  • SAPKK4 antibody
  • sek2 antibody
  • si:ch211-254d18.2 antibody

Protein level used designations for MAP2K7

mitogen-activated protein kinase kinase 7 , JNK kinase 2 , JNK-activating kinase 2 , JNKK 2 , MAP kinase kinase 7 , MAPK/ERK kinase 7 , MAPKK 7 , MEK 7 , c-Jun N-terminal kinase kinase 2 , dual specificity mitogen-activated protein kinase kinase 7 , SAPK kinase 4 , stress-activated protein kinase kinase 4 , mitogen activated protein kinase kinase 7 , protein kinase, mitogen activated, kinase 7

787278 Bos taurus
100302082 Ovis aries
363855 Rattus norvegicus
5609 Homo sapiens
485004 Canis lupus familiaris
26400 Mus musculus
560913 Danio rerio
394391 Xenopus laevis
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