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MAP3K3 Antibodies

(Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively\; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
MAP3K3 antibody  (AA 1-220) MAP3K3 antibody  (AA 1-220) MAP3K3 antibody (AA 1-220) (ABIN7268652)

MAP3K3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

MAP3K3 antibody  (N-Term) MAP3K3 antibody  (N-Term) MAP3K3 antibody (N-Term) (ABIN3044008)

MAP3K3 Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

MAP3K3 antibody MAP3K3 antibody MAP3K3 antibody (ABIN7258882)

MAP3K3 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated

MAP3K3 Antibodies by Reactivity

Find MAP3K3 Antibodies for a variety of species such as anti-Mouse MAP3K3, anti-Human MAP3K3, anti-Rat MAP3K3. The species listed below are among those available. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Application

Find MAP3K3 Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Host

Find MAP3K3 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Binding Specificity

Find MAP3K3 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Clonality

Find available monoclonal or polyclonal MAP3K3 Antibodies. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Clone

Find MAP3K3 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MAP3K3 Antibodies by Conjugate

Find MAP3K3 Antibodies with a specific conjugate such as Biotin, APC, Alkaline Phosphatase (AP). The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MAP3K3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7268652
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3044008
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7258882
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7299350
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258264
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN517853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (1)
Cat. No. ABIN7187280
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7074682
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC (p)
Validations
  • (1)
Cat. No. ABIN7211414
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (1)
Cat. No. ABIN3185519
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268651
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN1534084
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN517852
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN517854
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN5534484
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our MAP3K3 Antibodies

Yang, Lai, Lai, Hsu, Kuo, Yu, Lin, Yang, Kuo, Wu, Chung: "Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways." in: Anticancer research, Vol. 30, Issue 6, pp. 2135-43, (2010) (PubMed).

Nakamura, Johnson: "PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 36989-92, (2003) (PubMed).

Huang, Yang, Lin, Walker, Cheng, Liu, Su: "Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3." in: Nature immunology, Vol. 5, Issue 1, pp. 98-103, (2003) (PubMed).

Uhlik, Abell, Johnson, Sun, Cuevas, Lobel-Rice, Horne, DellAcqua, Johnson: "Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock." in: Nature cell biology, Vol. 5, Issue 12, pp. 1104-10, (2003) (PubMed).

Ellinger-Ziegelbauer, Brown, Kelly, Siebenlist et al.: "Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 ..." in: The Journal of biological chemistry, Vol. 272, Issue 5, pp. 2668-74, (1997) (PubMed).

Aliases for MAP3K3 Antibodies

mitogen activated protein kinase kinase kinase 3 (Map3k3) Antibodies
mitogen-activated protein kinase kinase kinase 3 (MAP3K3) Antibodies
mitogen-activated protein kinase kinase kinase 3 (Map3k3) Antibodies
mitogen-activated protein kinase kinase kinase 3 (map3k3) Antibodies
AW548911 Antibodies
MAPKKK3 Antibodies
MEKK3 Antibodies
Mekk3 Antibodies
mKIAA4031 Antibodies
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