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Browse our anti-MAP3K12 (MAP3K12) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 12 Antibodies (MAP3K12)
On are 51 Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) Antibodies from 12 different suppliers available. Additionally we are shipping MAP3K12 Proteins (6) and many more products for this protein. A total of 62 MAP3K12 products are currently listed.
Delta1, DKFZp459K2433, DLK, DLK-1, FA1, map3k12, map3k12a, MEKK12, MGC151798, MUK, pG2, PK, Pref-1, PREF1, zgc:77370, ZOG, ZPK, ZPKP1
list all antibodies Gene Name GeneID UniProt
MAP3K12 8788 P80370
MAP3K12 25579 Q63796
MAP3K12 26404 Q60700

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Most Popular Reactivities for anti-MAP3K12 (MAP3K12) Antibodies

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anti-Human MAP3K12 Antibodies:

anti-Rat (Rattus) MAP3K12 Antibodies:

anti-Mouse (Murine) MAP3K12 Antibodies:

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Top referenced anti-MAP3K12 Antibodies

  1. Human Polyclonal MAP3K12 Primary Antibody for IHC (p), WB - ABIN391319 : Itoh, Wang, Ito, Reddy, Itoh: SP3 acts as a positive regulator on the core promoter of human ZPK gene. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 7 references for ABIN391319

  2. Human Polyclonal MAP3K12 Primary Antibody for EIA, IHC (p) - ABIN359408 : Fukuyama, Yoshida, Yamashita, Deyama, Baba, Suzuki, Mohri, Ikezawa, Nakajima, Hirai, Ohno: MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN359408

  3. Human Polyclonal MAP3K12 Primary Antibody for IHC (p), WB - ABIN655162 : Yanai, Nakamura, Hijioka, Kamei, Ikari, Ishikawa, Shinozaki, Mizunuma, Hatake, Miyajima: Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. in Journal of biochemistry 2010 (PubMed)
    Show all 2 references for ABIN655162

More Antibodies against MAP3K12 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. Results suggest a potential signalling hierarchy between Delta-like 1 (show DLL1 Antibodies) and ephrin-B2 (show EFNB2 Antibodies) ligands, as neural stem cells adopt the Delta-like 1 (show DLL1 Antibodies) phenotype of stem cell maintenance on simultaneous presentation of both signals.

  2. The results indicate the occurrence of epimutation affecting the IG-DMR (show WDR20 Antibodies) and the MEG3 (show FAM129B Antibodies)-DMR (show WDR20 Antibodies) in the two cases, and imply that UPD (show UROD Antibodies)(14)mat and related (epi (show TFPI Antibodies))genetic aberrations constitute a rare but important underlying factor for Silver-Russell Syndrome

  3. Kaplan-Meier analysis indicated that higher DLK1 (show DLK1 Antibodies) levels were associated with shorter survival in Hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patients. These results suggest that the serum levels of DLK1 (show DLK1 Antibodies) may serve as a prognostic biomarker for HCC (show FAM126A Antibodies) patients.

  4. Notch (show NOTCH1 Antibodies) pathway activation in endothelial colony forming cells in vivo via co-implanted stromal cells expressing delta-like 1 (show DLL1 Antibodies) promotes vasculogenesis.

  5. Data show that the median expression of Jagged-1 (show JAG1 Antibodies) protein and delta-like 1 (show DLL1 Antibodies) protein (Dll-1 (show DLL1 Antibodies)) was significantly higher in acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)) blasts than in peripheral blood stem cells (PBSCs).

  6. miR (show MLXIP Antibodies)-130a inhibited the JNK (show MAPK8 Antibodies) pathway by targeting MAP3K12, contributing to its anti-apoptotic effect and the maintenance of diabetic endothelial progenitor cell function.

  7. DLK1 (show DLK1 Antibodies) expression diminishes during differentiation of human U937 cells to macrophages.

  8. Data show that preadipocyte factor 1 Pref-1 (show DLK1 Antibodies) is probably not a major contributor to gestational diabetes mellitus (GDM) pathophysiology but might directly contribute to triglycerides (TG) metabolism, as well as depend on gestational age and renal function.

  9. These mice show improved glucose tolerance. Taken together, we conclude Pref-1 (show DLK1 Antibodies) as a positive regulator of islet beta-cells and insulin (show INS Antibodies) production.

  10. Serum levels of Pref-1 (show DLK1 Antibodies) were associated with the amount of alcohol consumed during the past 30 days.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. Data assesses DLK's role in axons of adult, injured CNS neurons in vivo and shows that DLK (show DAPK3 Antibodies) does not appear to have a critical function in axonal degeneration; function appears restricted to soma

  2. This study provides compelling evidence for the pivotal roles of the ZPK/DLK and MKK4/MAP2K4 (show MAP2K4 Antibodies)-dependent mechanism in axotomy-induced motoneuron death in neonates

  3. DLK (show DAPK3 Antibodies)-inducible knockouts displayed a modest increase in basal synaptic transmission but had an attenuation of the JNK/c-Jun stress response pathway activation and significantly reduced neuronal degeneration after kainic acid-induced seizures.

  4. Abundance of DLK (show DAPK3 Antibodies) in turn controlled the levels of downstream JNK (show MAPK8 Antibodies) signaling and apoptosis.

  5. DLK (show DAPK3 Antibodies) is required for RGC JNK (show MAPK8 Antibodies) activation and cell death in a rodent model of optic neuropathy

  6. The cell intrinsic factors that determine whether a neuron regenerates or undergoes apoptosis in response to axonal injury are not well defined. DLK (show DAPK3 Antibodies) is an essential upstream mediator of both of these divergent outcomes in the same cell type.

  7. These data demonstrate that DLK (show DAPK3 Antibodies) enhances regeneration by promoting a retrograde injury signal that is required for the activation of the neuronal proregenerative program.

  8. The mixed lineage kinase dual leucine zipper kinase (DLK) selectively regulates the JNK (show MAPK8 Antibodies)-based stress response pathway to mediate axon degeneration and neuronal apoptosis without influencing other aspects of JNK (show MAPK8 Antibodies) signaling.

  9. ZPK/DLK plays a critical role in naturally occurring programmed cell death of motoneurons.

  10. This study indicated that the DLK (show DAPK3 Antibodies)-JNK (show MAPK8 Antibodies) pathway facilitates axon formation in neocortical neurons via stage-specific regulation of microtubule stability.

MAP3K12 Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Alternative names and synonyms associated with MAP3K12

  • mitogen-activated protein kinase kinase kinase 12 (map3k12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (MAP3K12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (map3k12-a) antibody
  • delta-like 1 homolog (Drosophila) (DLK1) antibody
  • mitogen activated protein kinase kinase kinase 12 (Map3k12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (Map3k12) antibody
  • Delta1 antibody
  • DKFZp459K2433 antibody
  • DLK antibody
  • DLK-1 antibody
  • FA1 antibody
  • map3k12 antibody
  • map3k12a antibody
  • MEKK12 antibody
  • MGC151798 antibody
  • MUK antibody
  • pG2 antibody
  • PK antibody
  • Pref-1 antibody
  • PREF1 antibody
  • zgc:77370 antibody
  • ZOG antibody
  • ZPK antibody
  • ZPKP1 antibody

Protein level used designations for MAP3K12

mitogen-activated protein kinase kinase kinase 12 , mitogen activated protein kinase kinase kinase 12 type A , fetal antigen 1 , preadipocyte factor 1 , protein delta homolog 1 , secredeltin , MAPK-upstream kinase , Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase) , Zipper (leucine) protein kinase , dual leucine zipper bearing kinase , dual leucine zipper kinase , leucine-zipper protein kinase , mixed lineage kinase , dual leucine zipper kinase DLK , leucine zipper protein kinase , protein kinase MUK , mitogen activated protein kinase kinase kinase 12 , zipper (leucine) protein kinase

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7786 Homo sapiens
26404 Mus musculus
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