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Browse our anti-MAP3K12 (MAP3K12) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 12 Antibodies (MAP3K12)
On are 54 Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) Antibodies from 13 different suppliers available. Additionally we are shipping MAP3K12 Proteins (6) and many more products for this protein. A total of 65 MAP3K12 products are currently listed.
Delta1, DKFZp459K2433, DLK, DLK-1, FA1, map3k12, map3k12a, MEKK12, MGC151798, MUK, pG2, PK, Pref-1, PREF1, zgc:77370, ZOG, ZPK, ZPKP1
list all antibodies Gene Name GeneID UniProt
MAP3K12 8788 P80370
MAP3K12 25579 Q63796
MAP3K12 26404 Q60700

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Most Popular Reactivities for anti-MAP3K12 (MAP3K12) Antibodies

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anti-Human MAP3K12 Antibodies:

anti-Rat (Rattus) MAP3K12 Antibodies:

anti-Mouse (Murine) MAP3K12 Antibodies:

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Top referenced anti-MAP3K12 Antibodies

  1. Human Polyclonal MAP3K12 Primary Antibody for IHC (p), WB - ABIN391319 : Itoh, Wang, Ito, Reddy, Itoh: SP3 acts as a positive regulator on the core promoter of human ZPK gene. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 7 references for ABIN391319

  2. Human Polyclonal MAP3K12 Primary Antibody for ELISA, WB - ABIN4332642 : Douziech, Laberge, Grondin, Daigle, Blouin: Localization of the mixed-lineage kinase DLK/MUK/ZPK to the Golgi apparatus in NIH 3T3 cells. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999 (PubMed)
    Show all 6 references for ABIN4332642

  3. Human Polyclonal MAP3K12 Primary Antibody for EIA, IHC (p) - ABIN359408 : Fukuyama, Yoshida, Yamashita, Deyama, Baba, Suzuki, Mohri, Ikezawa, Nakajima, Hirai, Ohno: MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN359408

  4. Human Polyclonal MAP3K12 Primary Antibody for IHC (p), WB - ABIN655162 : Yanai, Nakamura, Hijioka, Kamei, Ikari, Ishikawa, Shinozaki, Mizunuma, Hatake, Miyajima: Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. in Journal of biochemistry 2010 (PubMed)
    Show all 2 references for ABIN655162

  5. Human Polyclonal MAP3K12 Primary Antibody for IHC, IHC (p) - ABIN4332643 : Itoh, Horiuchi, Ikeda, Xu, Bannerman, Pleasure, Penninger, Tournier, Itoh: ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 (PubMed)

More Antibodies against MAP3K12 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. The study evaluated the roles of extracellular soluble DLK1 (show DLK1 Antibodies), comprising six EGF (show EGF Antibodies)-like domains and juxtamembrane regions, in human pancreatic cancer MIA (show MIA Antibodies) PaCa-2 cells in vitro and in vivo. Soluble DLK1 (show DLK1 Antibodies) exerted antitumor effects not only in cancer cell migration and anchorage-independent cell growth but also in in vivo tumor growth.

  2. Treatment of mice with recombinant human DLK1 (show DLK1 Antibodies) during pregnancy has significant effects on AT of the offspring. This can be associated with counter-regulatory changes in the Notch1 (show NOTCH1 Antibodies) signaling cascade.

  3. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1 (show DLK1 Antibodies)) self interacts

  4. Pref-1 (show DLK1 Antibodies) induces insulin (show INS Antibodies) synthesis and secretion via two independent pathways

  5. REVIEW: Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase

  6. Data from longitudinal, nested case-control study conducted in rural South Korea suggest that low serum levels of DLK1 (preadipocyte factor 1 (show DLK1 Antibodies)) may be useful biomarker for identifying women (but not men) at high risk of developing insulin (show INS Antibodies) resistance, prediabetes, and type 2 diabetes.

  7. The appropriate timing of Dll1 (show DLL1 Antibodies) expression is critical for its oscillatory expression, pointing to the functional significance of Dll1 (show DLL1 Antibodies)-mediated oscillatory cell-cell interactions in the segmentation clock. [review]

  8. Results suggest a potential signalling hierarchy between Delta-like 1 (show DLL1 Antibodies) and ephrin-B2 (show EFNB2 Antibodies) ligands, as neural stem cells adopt the Delta-like 1 (show DLL1 Antibodies) phenotype of stem cell maintenance on simultaneous presentation of both signals.

  9. The results indicate the occurrence of epimutation affecting the IG-DMR (show WDR20 Antibodies) and the MEG3 (show FAM129B Antibodies)-DMR (show WDR20 Antibodies) in the two cases, and imply that UPD (show UROD Antibodies)(14)mat and related (epi (show TFPI Antibodies))genetic aberrations constitute a rare but important underlying factor for Silver-Russell Syndrome

  10. Kaplan-Meier analysis indicated that higher DLK1 (show DLK1 Antibodies) levels were associated with shorter survival in Hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patients. These results suggest that the serum levels of DLK1 (show DLK1 Antibodies) may serve as a prognostic biomarker for HCC (show FAM126A Antibodies) patients.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. the prevention of the nuclear localization of DLK (show DAPK3 Antibodies) as induced by prediabetic signals with consecutive suppression of beta-cell apoptosis might constitute a novel target in the therapy of diabetes mellitus

  2. Data assesses DLK's role in axons of adult, injured CNS neurons in vivo and shows that DLK (show DAPK3 Antibodies) does not appear to have a critical function in axonal degeneration; function appears restricted to soma

  3. This study provides compelling evidence for the pivotal roles of the ZPK/DLK and MKK4/MAP2K4 (show MAP2K4 Antibodies)-dependent mechanism in axotomy-induced motoneuron death in neonates

  4. DLK (show DAPK3 Antibodies)-inducible knockouts displayed a modest increase in basal synaptic transmission but had an attenuation of the JNK/c-Jun stress response pathway activation and significantly reduced neuronal degeneration after kainic acid-induced seizures.

  5. Abundance of DLK (show DAPK3 Antibodies) in turn controlled the levels of downstream JNK (show MAPK8 Antibodies) signaling and apoptosis.

  6. DLK (show DAPK3 Antibodies) is required for RGC JNK (show MAPK8 Antibodies) activation and cell death in a rodent model of optic neuropathy

  7. The cell intrinsic factors that determine whether a neuron regenerates or undergoes apoptosis in response to axonal injury are not well defined. DLK (show DAPK3 Antibodies) is an essential upstream mediator of both of these divergent outcomes in the same cell type.

  8. These data demonstrate that DLK (show DAPK3 Antibodies) enhances regeneration by promoting a retrograde injury signal that is required for the activation of the neuronal proregenerative program.

  9. The mixed lineage kinase dual leucine zipper kinase (DLK) selectively regulates the JNK (show MAPK8 Antibodies)-based stress response pathway to mediate axon degeneration and neuronal apoptosis without influencing other aspects of JNK (show MAPK8 Antibodies) signaling.

  10. ZPK/DLK plays a critical role in naturally occurring programmed cell death of motoneurons.

MAP3K12 Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Alternative names and synonyms associated with MAP3K12

  • mitogen-activated protein kinase kinase kinase 12 (map3k12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (MAP3K12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (map3k12-a) antibody
  • delta-like 1 homolog (Drosophila) (DLK1) antibody
  • mitogen activated protein kinase kinase kinase 12 (Map3k12) antibody
  • mitogen-activated protein kinase kinase kinase 12 (Map3k12) antibody
  • Delta1 antibody
  • DKFZp459K2433 antibody
  • DLK antibody
  • DLK-1 antibody
  • FA1 antibody
  • map3k12 antibody
  • map3k12a antibody
  • MEKK12 antibody
  • MGC151798 antibody
  • MUK antibody
  • pG2 antibody
  • PK antibody
  • Pref-1 antibody
  • PREF1 antibody
  • zgc:77370 antibody
  • ZOG antibody
  • ZPK antibody
  • ZPKP1 antibody

Protein level used designations for MAP3K12

mitogen-activated protein kinase kinase kinase 12 , mitogen activated protein kinase kinase kinase 12 type A , fetal antigen 1 , preadipocyte factor 1 , protein delta homolog 1 , secredeltin , MAPK-upstream kinase , Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase) , Zipper (leucine) protein kinase , dual leucine zipper bearing kinase , dual leucine zipper kinase , leucine-zipper protein kinase , mixed lineage kinase , dual leucine zipper kinase DLK , leucine zipper protein kinase , protein kinase MUK , mitogen activated protein kinase kinase kinase 12 , zipper (leucine) protein kinase

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8788 Homo sapiens
25579 Rattus norvegicus
7786 Homo sapiens
26404 Mus musculus
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