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MAP3K12 antibody (C-Term)

MAP3K12 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359408
  • Target See all MAP3K12 Antibodies
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Binding Specificity
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 19
    • 12
    Human, Mouse
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K12 antibody is un-conjugated
    Application
    • 18
    • 18
    • 11
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects MAP3K12 at C-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAP3K12 Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Alternative Name
    MAP3K12 (MAP3K12 Products)
    Synonyms
    DLK antibody, MEKK12 antibody, MUK antibody, ZPK antibody, ZPKP1 antibody, PK antibody, Zpk antibody, zgc:77370 antibody, MGC151798 antibody, dlk antibody, map3k12 antibody, map3k12a antibody, mekk12 antibody, muk antibody, zpk antibody, zpkp1 antibody, DKFZp459K2433 antibody, map3k12-a antibody, map3k12-b antibody, map3k12b antibody, mitogen-activated protein kinase kinase kinase 12 antibody, mitogen activated protein kinase kinase kinase 12 antibody, mitogen-activated protein kinase kinase kinase 12 S homeolog antibody, mitogen-activated protein kinase kinase kinase 12 L homeolog antibody, MAP3K12 antibody, Map3k12 antibody, map3k12 antibody, map3k12.S antibody, map3k12.L antibody
    Background
    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.Synonyms: Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase
    Molecular Weight
    93188 Da
    Gene ID
    7786, 9606
    UniProt
    Q12852
    Pathways
    MAPK Signaling
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