MAP3K12 antibody (AA 828-859)

Catalog No. ABIN1539909

The Mouse Monoclonal anti-MAP3K12 antibody (Clone 473CT23-12-5) (ABIN1539909) specifically detects MAP3K12 in WB. The antibody is reactive with Human samples.

Quick Overview for MAP3K12 antibody (AA 828-859) (ABIN1539909)

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP3K12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 473CT23-12-5

Product Details anti-MAP3K12 Antibody

Binding Specificity: AA 828-859

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MAP3K12 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from human MAP3K12.

Isotype: IgG1

Application Details

Application Notes: WB: 1:100~250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MAP3K12 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MAP3K12

Target: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Alternative Name: MAP3K12

Background: This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq].

Molecular Weight: 93219

Gene ID: 7786

NCBI Accession: NP_001180440, NP_006292

UniProt: Q12852

Pathways: MAPK Signaling