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Browse our anti-HSD11B1 (HSD11B1) Antibodies

Full name:
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 Antibodies (HSD11B1)
On www.antibodies-online.com are 112 Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Antibodies from 21 different suppliers available. Additionally we are shipping HSD11B1 Kits (34) and HSD11B1 Proteins (14) and many more products for this protein. A total of 172 HSD11B1 products are currently listed.
Synonyms:
11-beta-HSD1, 11-DH, CORTRD2, HDL, hsd11, hsd11b, HSD11L, LRRGT00065, SDR26C1
list all antibodies Gene Name GeneID UniProt
HSD11B1 3290 P28845
HSD11B1 15483 P50172
HSD11B1 25116 P16232

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Most Popular Reactivities for anti-HSD11B1 (HSD11B1) Antibodies

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anti-Human HSD11B1 Antibodies:

anti-Mouse (Murine) HSD11B1 Antibodies:

anti-Rat (Rattus) HSD11B1 Antibodies:

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Top referenced anti-HSD11B1 Antibodies

  1. Cow (Bovine) Polyclonal HSD11B1 Primary Antibody for IHC, WB - ABIN2773867 : Paulsen, Nielsen, Richelsen, Bruun, Flyvbjerg, Pedersen: Upregulation of adipose 11-beta-hydroxysteroid dehydrogenase type 1 expression in ovariectomized rats is due to obesity rather than lack of estrogen. in Obesity (Silver Spring, Md.) 2008 (PubMed)
    Show all 3 references for ABIN2773867

  2. Human Polyclonal HSD11B1 Primary Antibody for ELISA, WB - ABIN185329 : Paterson, Morton, Fievet, Kenyon, Holmes, Staels, Seckl, Mullins: Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 3 references for ABIN185329

  3. Human Polyclonal HSD11B1 Primary Antibody for IF (p), IHC (p) - ABIN750913 : Nakata, Umeda, Masuzaki, Sawai: The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats. in BMC oral health 2016 (PubMed)

  4. Mouse (Murine) Polyclonal HSD11B1 Primary Antibody for ELISA, WB - ABIN4276641 : Sinclair, Walker, Burdon, van Beek, Kema, Hughes, Murray, Nightingale, Stewart, Rauz, Tomlinson: Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation? in The Journal of clinical endocrinology and metabolism 2010 (PubMed)

  5. Human Polyclonal HSD11B1 Primary Antibody for WB - ABIN374673 : Chang, Zheng, Hawkins, Isaacs, Wiley, Turner, Carpten, Bleecker, Walsh, Trent, Meyers, Isaacs, Xu: Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility. in Cancer research 2002 (PubMed)

More Antibodies against HSD11B1 Interaction Partners

Human Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) interaction partners

  1. Increased 11beta-HSD1 expression and its reductase activity in granulosa cells are the major causes of increased cortisol concentration in the follicular fluid of PCOS with insulin (show INS Antibodies) resistance.

  2. Reciprocal regulation of the glucocorticoid metabolizing enzymes, 11beta-hydroxysteroid dehydrogenase types 1 and 2, is associated with steroid-responsiveness and disease remission in childhood nephrotic syndrome.

  3. increased cortisol and 11beta-HSD1 abundance and decreased LOX (show LOX Antibodies) abundance were observed in human amnion tissue after the labor-initiated spontaneous rupture of membranes

  4. These findings indicated that 11beta-HSD1 inhibition can give a potential benefit in reducing obesity and lowering insulin (show INS Antibodies) resistance by modulating the insulin (show INS Antibodies)-signaling pathway and adipocytokine production.

  5. Review of the role of HSD11B1 in pregnancy complications, fetal diseases, and later life morbidity.

  6. hyperactive hypothalamo-pituitary-adrenocortical axis in overweight diabetic subjects may be associated with downregulation of 11beta-HSD1, MR, and GR in the brain.

  7. ins4436A in the HSD11B1 gene is associated with essential hypertension in a Polish population

  8. the availability of H6PDH determines the different direction of 11beta-HSD1 in liver and Leydig cells.

  9. we also found a significant difference between AA and AG genotype of rs6688832 and the AG genotype was associated with hyperandrogenism, but no statistical different distribution of polymorphism rs17368528 of H6PD and rs846908 of HSD11B1 were observed

  10. 11beta-HSD1 expressed in polyp-derived epithelial cells may be involved in the anti-inflammatory function of glucocorticoid in the treatment of nasal polyps, which contributes to increased levels of endogenous cortisol.

Pig (Porcine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) interaction partners

  1. Results describe the cloning, sequence and expression of 11beta-hydroxysteroid dehydrogenase type 1 from pig testis.

  2. concluded that the 11beta-hydroxysteroid dehydrogenase (11beta-HSD1 and 2) system is involved in the regulation of cortisol activity in the testis and thus in the regulation of spermatogenesis

  3. Effects of age, weaning and/or social isolation on the expression of genes regulating HSD11B1.

Cow (Bovine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) interaction partners

  1. HSD11B1 was localized in mature adipocytes of early lactating cows, indicating that circulating glucocorticoids promote effects other than differentiation.

  2. investigation of gene expression for 11HSD1, 11HSD2 (show HSD11B2 Antibodies), and glucocorticoid receptor (show NR3C1 Antibodies) in granulosa cells and theca interna layers during follicular maturation and atresia: expression of 11HSD1 is developmentally regulated in maturing follicles

  3. PGF2alpha but not PGE2 increases HSD11B1 bioactivity and protein expression by stimulating a posttranscriptional mechanism in stromal cells.

Mouse (Murine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) interaction partners

  1. 11beta-HSD1-deficient mice are not protected from metabolic disease or hepatosteatosis in the face of a nonalcoholic fatty liver disease-inducing diet.

  2. 11beta-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.

  3. these data suggest that corticosterone activation by 11beta-HSD1 in keratinocytes suppresses hapten-induced irritant dermatitis through suppression of expression of cytokines

  4. Nr3c2 (show NR3C2 Antibodies) has a role in mouse skin development in a process that involves HSD11B1/HSD11B2 (show HSD11B2 Antibodies)

  5. Loss of 11beta-HSD1 is associated with hepatocellular carcinoma.

  6. These findings suggest that 11beta-HSD1 may contribute to the decline in Npas4 (show NPAS4 Antibodies) and Arc (show NOL3 Antibodies) mRNA levels associated with memory impairment during ageing

  7. Our results demonstrate an inhibitory effect of IGF-I (show IGF1 Antibodies) on 11beta-HSD1 expression and activity within the pancreatic islets, which may mediate part of the IGF-I (show IGF1 Antibodies) effects on cell proliferation, survival and insulin (show INS Antibodies) secretion

  8. Data indicate that 11beta-HSD1 activity contributes substantially to diurnal and stress-induced increases in hippocampal CORT (show CORT Antibodies) levels.

  9. Dynamic increases in hippocampal 11b-HSD1 (show SPAG8 Antibodies) regenerated CORT (show CORT Antibodies) levels during learning and retrieval play a key role in age- and stress-associated impairments of spatial memory.

  10. Data suggest that Hsd11b1 expression is up-regulated in white adipose tissues of obese mice; this induction of Hsd11b1 appears to reduce mitochondrial respiration and adiponectin (show ADIPOQ Antibodies) synthesis in hypertrophic adipocytes.

HSD11B1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with HSD11B1

  • hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1) antibody
  • Corticosteroid 11-beta-dehydrogenase isozyme 1-like (LOC100342395) antibody
  • hydroxysteroid (11-beta) dehydrogenase 1 (hsd11b1) antibody
  • hydroxysteroid (11-beta) dehydrogenase 1 (Hsd11b1) antibody
  • hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) antibody
  • 11-beta-HSD1 antibody
  • 11-DH antibody
  • CORTRD2 antibody
  • HDL antibody
  • hsd11 antibody
  • hsd11b antibody
  • HSD11L antibody
  • LRRGT00065 antibody
  • SDR26C1 antibody

Protein level used designations for HSD11B1

11-beta-hydroxysteroid dehydrogenase 1 , hydroxysteroid 11-beta dehydrogenase 1 , hydroxysteroid (11-beta) dehydrogenase 1 , corticosteroid 11-beta-dehydrogenase isozyme 1 , short chain dehydrogenase/reductase family 26C, member 1 , 11-DH , 11-beta-HSD1 , 11-beta-hydroxysteroid dehydrogenase type 1 , 11-beta hydroxysteroid dehydrogenase , 11 beta-hydroxysteroid dehydrogenase type 1 , 7-alpha-HCD , 7-alpha-hydroxycholesterol dehydrogenase , 11beta-HSD-1 , 11beta-HSD1A , 11beta-hydroxysteroid dehydrogenase type 1 , Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A) , cortocosteroid 11-beta dehydrogenase , hydroxysteroid dehydrogenase, 11 beta type 1

GENE ID SPECIES
457698 Pan troglodytes
574322 Macaca mulatta
419861 Gallus gallus
100342395 Oryctolagus cuniculus
3290 Homo sapiens
443409 Ovis aries
379497 Xenopus laevis
449023 Canis lupus familiaris
397480 Sus scrofa
282589 Bos taurus
101835279 Mesocricetus auratus
15483 Mus musculus
25116 Rattus norvegicus
100135542 Cavia porcellus
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