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HSD11B1 antibody (Hydroxysteroid (11-Beta) Dehydrogenase 1) (AA 201-292) Primary Antibody

HSD11B1 Reactivity: Human, Mouse, Rat, Horse ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Pubmed (2)
Catalog No. ABIN750913
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    HSD11B1
    Binding Specificity
    • 8
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-292
    Reactivity
    • 57
    • 30
    • 25
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse
    Host
    • 48
    • 14
    • 4
    Rabbit
    Clonality
    • 57
    • 9
    Polyclonal
    Conjugate
    • 33
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HSD11B1 antibody is un-conjugated
    Application
    • 47
    • 30
    • 16
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Cow, Dog, Pig, Rabbit, Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HSD11B1
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Nakata, Umeda, Masuzaki, Sawai: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, 2016 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Further details: Sample: maxillary bones

    Xu, Zhao, Lin, Xiang, Wang, Ye, Huang: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, 2014 (PubMed). Method employed by authors: Immunohistochemistry (IHC)

  • Target
    HSD11B1
    Alternative Name
    HSD11B1/HSD1 (HSD11B1 Antibody Abstract)
    Synonyms
    11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hsd11, hsd11b, LRRGT00065, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid (11-beta) dehydrogenase 1b, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog, HSD11B1, HSD11B1b, hsd11b1.L, Hsd11b1
    Background

    Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: HDL, 11-DH, HSD11, HSD11B, HSD11L, CORTRD2, SDR26C1, 11-beta-HSD1, Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-beta-hydroxysteroid dehydrogenase 1, HSD11B1

    Gene ID
    3290
    UniProt
    P28845
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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