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Browse our Growth Hormone Receptor Proteins (GHR)

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Growth Hormone Receptor Proteins (GHR)
On www.antibodies-online.com are 62 Growth Hormone Receptor (GHR) Proteins from 11 different suppliers available. Additionally we are shipping Growth Hormone Receptor Antibodies (83) and Growth Hormone Receptor Kits (45) and many more products for this protein. A total of 199 Growth Hormone Receptor products are currently listed.
Synonyms:
AA986417, BVRB, FLR, GHBP, ghr, GHR/BP, SDR43U1
list all proteins Gene Name GeneID UniProt
GHR 645 P30043
GHR 25235 P16310
GHR 14600 P16882

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Growth Hormone Receptor Proteins (GHR) by Origin

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Top referenced Growth Hormone Receptor Proteins

  1. Rat (Rattus) Growth Hormone Receptor Protein expressed in Human Cells - ABIN2009065 : Leung, Spencer, Cachianes, Hammonds, Collins, Henzel, Barnard, Waters, Wood: Growth hormone receptor and serum binding protein: purification, cloning and expression. in Nature 1988 (PubMed)
    Show all 6 references for ABIN2009065

  2. Human Growth Hormone Receptor Protein expressed in HEK-293 Cells - ABIN2181160 : Ghizzoni, Duquesnoy, Torresani, Vottero, Goossens, Bernasconi: Isolated growth hormone deficiency type IA associated with a 45-kilobase gene deletion within the human growth hormone gene cluster in an Italian family. in Pediatric research 1995 (PubMed)
    Show all 3 references for ABIN2181160

More Proteins for Growth Hormone Receptor Interaction Partners

Human Growth Hormone Receptor (GHR) interaction partners

  1. GHR exon 3 genotype appears to have no clinical significance, at least in Brazilian acromegaly patients.

  2. No differences were observed in GHR genotype distribution between the idiopathic growth hormone (show GH1 Proteins) deficiency (IGHD)patients and the control group. Patients with IGHD did not differ among each other depending on their genotype (fl/fl (show FLT3LG Proteins)-GHR or fl/d3-GHR) in terms of growth velocity before introducing therapy or growth rate after one year of recombinant human GH therapy.

  3. miR (show MLXIP Proteins)-127-5p suppressed NF-kappaB (show NFKB1 Proteins) activity by directly targeting BLVRB (show BLVRB Proteins) in hepatocellular carcinoma cells.

  4. GHR-exon 3 polymorphisms did not show any consistent association with clinical and laboratory features of acromegalic patients even after treatment.

  5. We report a rapid, optimized method for genotyping the GHR full-length versus exon 3-deleted isoform (GHRd3)

  6. Data indicate that growth hormone binding protein (GHR) and KCNQ1 (show KCNQ1 Proteins) potassium channel (show KCNAB2 Proteins) variants with large effects on stature.

  7. Association between GHR/exon-3 variants and serum GH, IGF-1 (show IGF1 Proteins) and IGFBP-3 (show IGFBP3 Proteins) levels in diabetes and coronary heart disease.

  8. Data suggest that isoenzymes BVRA (show BLVRA Proteins) and BVRB (show BLVRB Proteins) play different roles in energy metabolism and in pathogenesis of abdominal obesity and hypertriglyceridemia. [REVIEW]

  9. Data suggest that cell membrane/lipid bilayer binding of GHR intracellular domain is independent of transient changes in protein secondary structure of GHR.

  10. The d3-GHR variant genotype did not have an effect on clinical features or comorbidity in acromegalic patients, but it might play a role in GH/IGF-1 (show IGF1 Proteins) level discordance in acromegaly.

Rabbit Growth Hormone Receptor (GHR) interaction partners

  1. Fos-zippered GHR tails and Jak2 (show JAK2 Proteins), both purified from baculovirus-infected insect cells, interacted via box1 with a binding affinity of approximately 40nM.

  2. Jak2 (show JAK2 Proteins) binding to the growth hormone receptor prevents endocytosis in a non-catalytic manner

  3. GHR gene may be a candidate gene responsible for butcher trait in rabbit.

Pig (Porcine) Growth Hormone Receptor (GHR) interaction partners

  1. GHR double-allelic knockout pigs were 50% smaller than that of the controls.

  2. Growth hormone (GH (show GH1 Proteins)) in maturation medium did not increase cumulus expansion in porcine cumulus-oocyte complexes but did improve nuclear maturation, GH had no effect on porcine fertilization and embryo development.

  3. subunit alignment is critical for effective signaling in GH receptor activation

Cow (Bovine) Growth Hormone Receptor (GHR) interaction partners

  1. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 (show STAT5A Proteins) ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  2. hepatic growth hormone receptor and suppressor of cytokine signaling (SOCS (show CISH Proteins))2 (show SOCS2 Proteins) messenger RNA expression appeared to be promptly and sensitively regulated by increased estradiol levels before ovulation of dairy heifers

  3. Comparatively studied genetic diversity of growth hormone receptor (GHR) in Tibetan cattle and Chinese Holstein cow.

  4. This work confirms the importance of CAPN1 (show CAPNL1 Proteins) and CAST for tenderness in beef, provides a new effect of CAST on beef tenderness, and questions the utility of GHR as a selection marker for beef quality.

  5. the data support the high potential of the growth hormone receptor F279Y polymorphism as a marker for the improvement of milk traits in selection programs

  6. 6 of the published GHR SNPs and 7 of the novel GHR SNPs were associated with at least 1 of the traits--milk yield, fat yield, protein yield, fat percentage, protein percentage, somatic cell score, calving interval, survival and growth and size traits.

  7. Effects of GHR p.Phe279Tyr mutations on milk, fat and protein yield, as well as fat and protein percentage in the milk of 1222 Holstein cows was found to be significantly associated with protein percentage.

  8. Food deprivation-induced decrease in circulating IGF-I (show IGF1 Proteins) in steers is associated with decrease in expression of different IGF-I (show IGF1 Proteins) mRNA variants and specific decrease in expression of growth hormone receptor mRNA variants 1C3 and 1A in liver.

  9. Insulin (show INS Proteins) regulates the efficiency of GH signaling in liver and adipose tissue of dairy cows by acting as a rheostat of GHR synthesis.

  10. Results show that chicken ovalbumin upstream promoter transcription factor (show NR2F1 Proteins) II (COUP-TFII (show NR2F2 Proteins)), hepatocyte nuclear factor 4alpha (HNF-4alpha (show HNF4A Proteins)) and HNF-4gamma regulate growth hormone receptor 1A promoter activity by binding to a common DNA element

Mouse (Murine) Growth Hormone Receptor (GHR) interaction partners

  1. disruption of cardiomyocyte GH-induced signaling in adult GhrKO mice does not affect cardiac function, but it does play a role in systemic glucose homeostasis, in part through modulation of circulating IGF-1 (show IGF1 Proteins).

  2. Snell, GHKRO, and PAPPA (show PAPPA Proteins)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT Proteins)) and N-myc downstream-regulated gene 1 (NDRG1 (show NDRG1 Proteins)).

  3. adult-onset growth hormone receptor knockout mice (aGHRKO mice), like GHRKO animals, displayed retarded growth and high adiposity with improved insulin (show INS Proteins) sensitivity. Importantly, female aGHRKO animals showed an increase in their maximal lifespan, whereas the lifespan of male aGHRKO mice was not different from controls.

  4. Similar to other mice with decreased GH action, female GHA mice display reduced age-related lipid redistribution and improved insulin (show INS Proteins) sensitivity, but no change in cellular senescence.

  5. The dwarf (show POU1F1 Proteins) phenotype was partially corrected via plasmid containing the growth hormone (show GH1 Proteins) gene administrated intramuscularly, depending on age at treatment.

  6. GHR-dependent downregulation of NLRP3 (show NLRP3 Proteins) inflammasome in macrophages is linked to pro-longevity effects that maintain immune system homeostasis in aging.

  7. both brown adipose tissue (BAT (show BAAT Proteins)) and white adipose tissue (WAT) contribute in different ways to phenotypes in GHRKO mice, with Ghr ablation blunting inflammation in BAT (show BAAT Proteins) as well as cellular metabolism and mitochondrial biogenesis in WAT

  8. Data (including data from studies in knockout mice) suggest Socs2 (suppressor of cytokine signaling 2 (show SOCS2 Proteins)) regulates liver regeneration rate after partial hepatectomy, Ghr level via ubiquitination/proteolysis, and serum Igf1 (insulin-like growth factor-1 (show IGF1 Proteins)).

  9. It was concluded that endogenously secreted PTH (show PTH Proteins) and GHR signaling in bone are necessary to establish radial bone growth and optimize mineral acquisition during growth.

  10. removal of GHR in muscle of male MuGHRKO mice replicates some of the health benefits seen in global GHR-/- mice including improvements to glucose homeostasis and smaller body weight in males

Growth Hormone Receptor (GHR) Protein Profile

Protein Summary

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Growth Hormone Receptor (GHR)

  • growth hormone receptor (ghr)
  • growth hormone receptor (GHR)
  • growth hormone receptor (LOC100304685)
  • biliverdin reductase B (flavin reductase (NADPH)) (BLVRB)
  • growth hormone receptor (Ghr)
  • AA986417 protein
  • BVRB protein
  • FLR protein
  • GHBP protein
  • ghr protein
  • GHR/BP protein
  • SDR43U1 protein

Protein level used designations for Growth Hormone Receptor Proteins (GHR)

somatotropin receptor , growth hormone receptor , BVR-B , FR , GHBP , NADPH-dependent diaphorase , NADPH-flavin reductase , biliverdin-IX beta-reductase , flavin reductase (NADPH) , green heme-binding protein , short chain dehydrogenase/reductase family 43U, member 1 , GH receptor , growth hormone binding protein , serum binding protein , growth hormone receptor precursor splice variant D56 , growth hormone receptor variant d5-6 , growth hormone receptor/binding protein , Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein) , growth hormone-binding protein , serum-binding protein , Somatotropin receptor

GENE ID SPECIES
398153 Xenopus laevis
471560 Pan troglodytes
554180 Monodelphis domestica
100126695 Papio anubis
100144349 Oryzias latipes
100304685 Ictalurus punctatus
100451189 Pongo abelii
100600868 Nomascus leucogenys
645 Homo sapiens
2690 Homo sapiens
100009325 Oryctolagus cuniculus
25235 Rattus norvegicus
397488 Sus scrofa
408184 Gallus gallus
403721 Canis lupus familiaris
280805 Bos taurus
14600 Mus musculus
100135527 Cavia porcellus
443333 Ovis aries
697986 Macaca mulatta
100422780 Ailuropoda melanoleuca
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