Growth Hormone Receptor Protein (GHR) (AA 27-264) (His tag)
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- Target See all Growth Hormone Receptor (GHR) Proteins
- Growth Hormone Receptor (GHR)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-264
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Growth Hormone Receptor protein is labelled with His tag.
- Purpose
- Human GHR/Growth Hormone R Protein
- Sequence
- Ala27-Tyr264
- Characteristics
- Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Growth Hormone Receptor (GHR) (AA 27-264) (Active) protein (His tag)
GHR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Growth Hormone Receptor (GHR) protein (Fc Tag)GHR Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Growth Hormone Receptor (GHR) (AA 19-118) protein (GST tag)GHR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Hormone Receptor (GHR) (Active) protein (His tag)GHR Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (Fc Tag)GHR Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (His tag,Fc Tag)GHR Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (His tag)GHR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (AA 289-638) protein (His tag)Crystallography grade GHR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Growth Hormone Receptor (GHR) (AA 25-273) protein (His tag)Crystallography grade GHR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Growth Hormone Receptor (GHR) (AA 298-650) protein (His tag)Crystallography grade GHR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Growth Hormone Receptor (GHR)
- Alternative Name
- GHR (GHR Products)
- Synonyms
- GHBP Protein, AA986417 Protein, GHR/BP Protein, GHR Protein, ghr Protein, ghr.a Protein, zgc:162141 Protein, growth hormone receptor Protein, growth hormone receptor L homeolog Protein, growth hormone receptor a Protein, GHR Protein, Ghr Protein, ghr.L Protein, ghr Protein, ghra Protein
- Background
- Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
- Molecular Weight
- 28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
- Pathways
- NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus
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