IL1RN Proteins
(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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48 results
IL1RN
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
IL1RN
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
IL1RN
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
IL1RN
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE
1 image
IL1RN
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
IL1RN
Origin: Human
Host: HEK-293T Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
IL1RN
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1RN
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 97 % by SDS-PAGE.
Active
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
IL1RN
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
Animal-Free
IL1RN
Origin: Human, Mouse
Host: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1RN
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
IL1RN
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
IL1RN
Origin: Rhesus Monkey
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
Latest Publications for our IL1RN Proteins
: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." in: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).
: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." in: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).
: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).
: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).
: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).
: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." in: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).
Aliases for IL1RN Proteins
interleukin 1 receptor antagonist (IL1RN) Proteinsinterleukin 1 receptor antagonist (Il1rn) Proteins
interleukin 1 receptor antagonist-like (IL1RNL) Proteins
DIRA Proteins
F630041P17Rik Proteins
ICIL-1RA Proteins
IL-1ra Proteins
IL-1RA Proteins
IL-1ra3 Proteins
IL-1RN Proteins
IL1F3 Proteins
IL1RA Proteins
IL1RN Proteins
IRAP Proteins
IRAP1 Proteins
MVCD4 Proteins
Did you look for something else?
- IL1RL2 Proteins
- IL1RL1 Proteins
- IL1RAPL2 Proteins
- IL1RAP Proteins
- IL1R2 Proteins
- IL1F9 Proteins
- IL1F10 Proteins
- IL1A Proteins
- IL18RAP Proteins
- IL18R1 Proteins
- IL18BP Proteins
- IL17RE Proteins
- IL17RD Proteins
- IL17RC Proteins
- IL17RA Proteins
- IL17F Proteins
- IL17D Proteins
- IL17C Proteins
- IL17B Proteins
- IL17 Receptor B Proteins
- IL2 Receptor beta Proteins
- IL20RA Proteins
- IL20RB Proteins
- IL21 Receptor Proteins
- IL22 Receptor alpha 1 Proteins
- IL22RA2 Proteins
- IL23 Proteins
- IL23A Proteins
- IL23R Proteins
- IL27 Receptor alpha Proteins
- IL28A Proteins
- IL28B Proteins
- IL28RA Proteins
- IL29 Proteins
- IL2RG Proteins
- IL31RA Proteins
- IL32 Proteins
- IL36A/IL1F6 Proteins
- IL3RA Proteins
- IL4 Receptor Proteins
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