Browse our anti-IRAK1 (IRAK1) Antibodies

On are 280 Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) Antibodies from 28 different suppliers available. Additionally we are shipping IRAK1 Kits (29) and IRAK1 Proteins (10) and many more products for this protein. A total of 332 IRAK1 products are currently listed.
AA408924, Il1rak, IRAK, IRAK-1, IRAK1, IRAK1-S, mPLK, pelle, Plpk, RGD1563841
list all antibodies Gene Name GeneID UniProt
IRAK1 3654 P51617
IRAK1 16179 Q62406
IRAK1 363520  

Most Popular Reactivities for anti-IRAK1 (IRAK1) Antibodies

anti-Human IRAK1 Antibodies:

anti-Mouse (Murine) IRAK1 Antibodies:

anti-Rat (Rattus) IRAK1 Antibodies:

All available anti-IRAK1 Antibodies

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More Antibodies against IRAK1 Interaction Partners

Human Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) interaction partners

  1. High IRAK1 expression is associated with multiple myeloma.

  2. TLR4 (show TLR4 Antibodies)- and TLR2 (show TLR2 Antibodies)-induced IRAK-ERK (show EPHB2 Antibodies) pathway cross-talks with p67phox (show NCF2 Antibodies)-Nox-2 (show CYBB Antibodies) for reactive oxygen species generation, thus regulating IL-1beta (show IL1B Antibodies) transcription and processing in monocytic cells.

  3. Data suggest that, in monocytes and macrophages, the interleukin-1B- (IL1B (show IL1B Antibodies))-stimulated trans-autophosphorylation of IRAK4 (interleukin-1 receptor-associated kinase 4 (show IRAK4 Antibodies)) is initiated by MYD88- (myeloid differentiation primary response gene 88 (show MYD88 Antibodies))-induced dimerization of IRAK4 (show IRAK4 Antibodies). In contrast, IRAK1 is inactive in unstimulated monocytes/macrophages and is converted to an active protein kinase (show CDK7 Antibodies) in response to IL1B (show IL1B Antibodies).

  4. Data indicate the complexity of interactions between Pin1 (show PIN1 Antibodies) and activated IRAK1, suggesting that phosphorylation of neighboring Ser (show SIGLEC1 Antibodies)/Thr (show TRH Antibodies)-Pro motifs in proteins might provide competitive advantage at cellular concentrations for engaging with Pin1 (show PIN1 Antibodies).

  5. IRAK1 is a direct target of miR (show MLXIP Antibodies)-146b and has functional roles to inhibit various aggressive papillary thyroid carcinoma cell activities.

  6. our data strongly suggest that AQCA-mediated suppression of inflammatory responses could be managed by a direct interference of signaling cascades including IRAK and Syk (show SYK Antibodies), linked to the activation of NF-kappaB (show NFKB1 Antibodies) and AP-1 (show FOSB Antibodies).

  7. The IRAK1 rs3027898 was not associated with RA, whereas C allele of miR (show MLXIP Antibodies)-146a rs2910164 was found to be protective.

  8. the Xq28 region containing TMEM187 (show TMEM187 Antibodies) and IRAK1 (rs13397, rs1059703, and rs1059702) with rheumatoid arthritis (RA)susceptibility; results replicated association of the 3 Xq28 polymorphisms with RA risk in Tunisian and French populations and suggested that RA susceptibility is associated with TMEM187 (show TMEM187 Antibodies)-IRAK1 polymorphisms in women

  9. IRAK1 expression was not significantly increased in tympanic membrane of otitis media patients.

  10. Our findings reveal that IRAK1 promotes cell survival and is an attractive therapeutic target in head and neck squamous cell carcinomas

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) interaction partners

  1. Data, including data from studies in knockout mice, suggest that Irak1 is involved in regulating glucose metabolism and insulin (show INS Antibodies) sensitivity in skeletal muscle (but not in liver and not in obesity due to high-fat diet); insulin (show INS Antibodies) sensitivity is 30% higher in Irak1 knockout mice on chow diet, but Irak1 deletion does not affect development of glucose intolerance due to high-fat diet.

  2. Suppression of IRAK1 or IRAK4 (show IRAK4 Antibodies) Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1 (show TNIP1 Antibodies)

  3. Torreya nucifera butanol fraction exhibits anti-inflammatory activities by direct inhibition of macrophage Src (show SRC Antibodies)/Syk (show SYK Antibodies)/NF-kappaB (show NFKB1 Antibodies) and IRAK1/AP-1 (show JUN Antibodies) signaling.

  4. IRAK1 is involved in TLR4 (show TLR4 Antibodies)-mediated downregulation of ABCA1 (show ABCA1 Antibodies) expression and lipid accumulation in VSMCs.

  5. plays an important role in intestinal inflammation by mediating T cell activation, differentiation, and accumulation in the gut (show GUSB Antibodies)

  6. Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-kappaB (show NFKB1 Antibodies) and MAPK (show MAPK1 Antibodies) pathways

  7. miR (show MLXIP Antibodies)-146a ameliorates liver ischemia/reperfusion injury in vivo and hypoxia/reoxygenation injury in vitro by directly suppressing IRAK1 and TRAF6 (show TRAF6 Antibodies).

  8. miR (show MLXIP Antibodies)-146a attenuates sepsis-induced cardiac dysfunction by preventing NF-kappaB (show NFKB1 Antibodies) activation, inflammatory cell infiltration, and inflammatory cytokine production via targeting of IRAK and TRAF6 (show TRAF6 Antibodies) in both cardiomyocytes and inflammatory monocytic cells.

  9. IRAK1 deficiency impacts multiple TLR-dependent pathways and decreases early cytokine responses following polymicrobial sepsis.

  10. CD40 (show CD40 Antibodies) signaling induces IRAK1 sumoylation in the presence of TNF receptor-associated factor 2 (TRAF2 (show TRAF2 Antibodies)) and intracellular isoform of osteopontin (show SPP1 Antibodies)

Cow (Bovine) Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) interaction partners

  1. Results describe a new full-length gene model for the bovine IRAK1 gene.

  2. ALOX5AP (show ALOX5AP Antibodies), CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.

IRAK1 Antigen Profile

Antigen Summary

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IRAK1

  • interleukin-1 receptor-associated kinase 1 (IRAK1) antibody
  • interleukin-1 receptor-associated kinase 1 (irak1) antibody
  • interleukin-1 receptor-associated kinase 1 (Irak1) antibody
  • AA408924 antibody
  • Il1rak antibody
  • IRAK antibody
  • IRAK-1 antibody
  • IRAK1 antibody
  • IRAK1-S antibody
  • mPLK antibody
  • pelle antibody
  • Plpk antibody
  • RGD1563841 antibody

Protein level used designations for IRAK1

interleukin-1 receptor-associated kinase 1 , IRAK-1 , Pelle homolog , interleukin-1 receptor-associated kinase-1 , pelle-like protein kinase , interleukin receptor associated kinase 1

465935 Pan troglodytes
569226 Danio rerio
3654 Homo sapiens
16179 Mus musculus
363520 Rattus norvegicus
492247 Canis lupus familiaris
396606 Sus scrofa
533953 Bos taurus
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