IRAK1 antibody (AA 405-433)

Catalog No. ABIN3028764

The Rabbit Polyclonal anti-IRAK1 antibody (ABIN3028764) specifically detects IRAK1 in WB, ELISA and FACS. The antibody is reactive with Mouse samples.

Quick Overview for IRAK1 antibody (AA 405-433) (ABIN3028764)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-IRAK1 Antibody

Binding Specificity: AA 405-433

Purpose: Irak1 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Alternative Name: Irak1

Background: Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.

UniProt: Q62406

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades