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IRAK1 Products

(Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Categories

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured IRAK1 Categories

IRAK1 Antibodies

High quality antibodies with extensive validation data.

IRAK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

IRAK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IRAK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (1)
Cat. No. ABIN1387749
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP, IF, RNAi
Validations
  • (9)
Cat. No. ABIN561510
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP, IF
Validations
  • (6)
Cat. No. ABIN561509
Quantity 100 μg
Datasheet Datasheet

Recommended IRAK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957194
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968044
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5691933
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended IRAK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5569838
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123626
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308057
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IRAK1 products

Chen, Tang, Fu, Wang, Han, Meng: "Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages." in: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1921-1931, (2018) (PubMed).

Abdel Motaleb, Nabih, Mohamed, Abd Elhalim: "Up-regulation of circulating miRNA146a correlates with viral load via IRAK1 and TRAF6 in hepatitis C virus-infected patients." in: Virus research, Vol. 238, pp. 24-28, (2018) (PubMed).

Teng, Luo, Yu, Chen, Huang, Chen, Xie, Zeng, Luo, Xiong, Liu, Hou, Feng: "CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells." in: Genes and immunity, (2018) (PubMed).

Yang, Zhou, Hu, Luo, Xie, Shen, Bian, Yin, Li, Zhang: "Ficolin-A/2, acting as a new regulator of macrophage polarization, mediates the inflammatory response in experimental mouse colitis." in: Immunology, Vol. 151, Issue 4, pp. 433-450, (2017) (PubMed).

Tosun, Fried, Niggemann, Zänker, Dittmar: "Hybrid Cells Derived from Human Breast Cancer Cells and Human Breast Epithelial Cells Exhibit Differential TLR4 and TLR9 Signaling." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).

Wen, Ji, Tang, Lin, Xiao, Liang, Wang, Su, Ferrandon, Li: "Positive Feedback Regulation between Transglutaminase 2 and Toll-Like Receptor 4 Signaling in Hepatic Stellate Cells Correlates with Liver Fibrosis Post Schistosoma japonicum Infection." in: Frontiers in immunology, Vol. 8, pp. 1808, (2017) (PubMed).

Ren, Sun, Deng, Zhang, Wu, Wei, Mani, Dou, Wang: "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015) (PubMed).

Liu, Wang, Qian, Li: "Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." in: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).

Jensen, Whitehead: "Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 3, pp. 1500-6, (2003) (PubMed).

Jiang, Johnson, Nie, Qin, Bird, Li et al.: "Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 ..." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 10952-6, (2003) (PubMed).

Synonyms and alternative names related to IRAK1

interleukin 1 receptor associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 1 (irak1), interleukin-1 receptor-associated kinase 1 (Irak1), AA408924, Il1rak, IRAK, IRAK-1, IRAK1, IRAK1-S, mPLK, pelle, Plpk, RGD1563841

Protein level used designations for IRAK1

  • interleukin-1 receptor-associated kinase 1
  • IRAK-1
  • Pelle homolog
  • interleukin-1 receptor-associated kinase-1
  • pelle-like protein kinase
  • interleukin receptor associated kinase 1
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