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Browse our anti-JAG2 (JAG2) Antibodies

Full name:
anti-Jagged 2 Antibodies (JAG2)
On www.antibodies-online.com are 98 Jagged 2 (JAG2) Antibodies from 19 different suppliers available. Additionally we are shipping JAG2 Proteins (15) and JAG2 Kits (9) and many more products for this protein. A total of 127 JAG2 products are currently listed.
Synonyms:
D12Ggc2e, HJ2, jag2, mJagged2-1, SER2, serB, Serh, sm, zgc:152855
list all antibodies Gene Name GeneID UniProt
JAG2 16450 Q9QYE5
JAG2 3714 Q9Y219
JAG2 29147  

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Most Popular Reactivities for anti-JAG2 (JAG2) Antibodies

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anti-Mouse (Murine) JAG2 Antibodies:

anti-Human JAG2 Antibodies:

anti-Rat (Rattus) JAG2 Antibodies:

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Top referenced anti-JAG2 Antibodies

  1. Human Monoclonal JAG2 Primary Antibody for IF - ABIN2663815 : Hellström, Phng, Hofmann, Wallgard, Coultas, Lindblom, Alva, Nilsson, Karlsson, Gaiano, Yoon, Rossant, Iruela-Arispe, Kalén, Gerhardt, Betsholtz: Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. in Nature 2007 (PubMed)
    Show all 6 references for ABIN2663815

  2. Human Monoclonal JAG2 Primary Antibody for FACS - ABIN2665211 : Luo, Aster, Hasserjian, Kuo, Sklar: Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. in Molecular and cellular biology 1997 (PubMed)
    Show all 6 references for ABIN2665211

  3. Mouse (Murine) Monoclonal JAG2 Primary Antibody for FACS - ABIN2665859 : Ehebauer, Chirgadze, Hayward, Martinez Arias, Blundell: High-resolution crystal structure of the human Notch 1 ankyrin domain. in The Biochemical journal 2005 (PubMed)
    Show all 5 references for ABIN2665859

  4. Mouse (Murine) Monoclonal JAG2 Primary Antibody for FACS - ABIN2663814 : Shimizu, Chiba, Hosoya, Kumano, Saito, Kurokawa, Kanda, Hamada, Hirai: Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2. in Molecular and cellular biology 2000 (PubMed)
    Show all 5 references for ABIN2663814

  5. Human Polyclonal JAG2 Primary Antibody for EIA, IHC (p) - ABIN358626 : Hayashi, Kageyama, Ishizaka, Xia, Kihara, Oshima: Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes. in Journal of andrology 2001 (PubMed)
    Show all 4 references for ABIN358626

  6. Human Polyclonal JAG2 Primary Antibody for IHC (p), WB - ABIN390090 : Cereseto, Tsai: Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division. in Journal of cellular physiology 2000 (PubMed)
    Show all 3 references for ABIN390090

  7. Chicken Polyclonal JAG2 Primary Antibody for WB - ABIN2782165 : Passos Gregorio, Gattaz, Tavares, Kieling, Timm, Wang, Berg Rasmussen, Werge, Dias-Neto: Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects. in Schizophrenia research 2006 (PubMed)
    Show all 2 references for ABIN2782165

More Antibodies against JAG2 Interaction Partners

Mouse (Murine) Jagged 2 (JAG2) interaction partners

  1. silencing prevents Notch2 (show NOTCH2 Antibodies)-driven osteoclast development and bone destruction in multiple myeloma

  2. Although Jag1 (show JAG1 Antibodies) shares a high degree of homology with Jag2 in the ectodomain region, BACE1 (show BACE Antibodies) fails to cleave Jag2 effectively, indicating a selective cleavage of Jag1 (show JAG1 Antibodies).

  3. Reducing Jagged 1 (show JAG1 Antibodies) and 2 levels prevents cerebral arteriovenous malformations in matrix Gla protein (show MGP Antibodies) deficiency.

  4. these findings suggest that Jagged2 signaling can affect graft acceptance by upregulation of IL-6 (show IL6 Antibodies) and consequent resistance to Treg-cell suppression.

  5. results demonstrate that maternal P4 levels during midpregnancy can inhibit the expression of Jagged2 and Notch1 (show NOTCH1 Antibodies), which are involved in primordial folliculogenesis, in the mouse fetal ovary

  6. These data suggest that Notch (show NOTCH1 Antibodies) ligands are differentially regulated in DCs: Delta-like (show DLK1 Antibodies) 4 is regulated by T helper cells and by pathogen-derived Th1 (show HAND1 Antibodies) stimuli, whereas Jagged 2 is regulated by Th2 cells and pathogen-derived Th2-promoting stimuli.

  7. novel Jagged2/miR (show MLXIP Antibodies)-200-dependent pathway that mediates lung adenocarcinoma epithelial-to-mesenchymal transition and metastasis

  8. Loss of Jagged2 is associated with craniofacial, limb, and T cell development.

  9. Notch (show NOTCH1 Antibodies) ligands, including Delta-like1 and 3 and Jagged1 (show JAG1 Antibodies) and Jagged2, show distinct expression patterns in the developing and adult brain overlapping that of Notch1 (show NOTCH1 Antibodies)

  10. Jagged2 stimulates the development of natural killer cells from Lin(-) Sca-1 (show Ly6a Antibodies)(+) c-kit (show KIT Antibodies)(+) hematopoietic stem cells

Human Jagged 2 (JAG2) interaction partners

  1. Immunohistochemistry showed a reverse correlation between MUC2 and Notch3 or Jagged1 (P = 0.033 and P = 0.005, respectively) and between MUC5AC and Jagged1 or Hes1

  2. Jagged-2 enhances immunomodulatory activity in adipose derived mesenchymal stem cells

  3. Increased expression of JAG2, a target of miR (show MLXIP Antibodies)-1280, is associated with high metastatic dissemination at diagnosis and a poor outcome in medulloblastoma.

  4. Results show that tumor cell migration, invasion, and metastasis are dependent on JAGGED2 independently of NOTCH (show NOTCH1 Antibodies) activation.

  5. silencing prevents Notch2 (show NOTCH2 Antibodies)-driven osteoclast development and bone destruction in multiple myeloma

  6. Although Jag1 (show JAG1 Antibodies) shares a high degree of homology with Jag2 in the ectodomain region, BACE1 (show BACE Antibodies) fails to cleave Jag2 effectively, indicating a selective cleavage of Jag1 (show JAG1 Antibodies).

  7. This study demonistrated that NOTCH (show NOTCH1 Antibodies) ligands JAG1 (show JAG1 Antibodies) and JAG2 as critical pro-survival factors in childhood medulloblastoma.

  8. Jagged2 expression status was closely correlated with important histopathologic characteristics (grades and stages) and the recurrence and metastasis of bladder urothelial carcinomas.

  9. Notch-1 (show NOTCH1 Antibodies) and Jagged-2 are not expressed in spastic colon segments, which may be associated with the pathogenesis of Hirschsprung disease.

  10. JAG2-mediated Notch (show NOTCH1 Antibodies) activation confers phenotypic and functional aspects of Langerhans cell histiocytosis to dendritic cells.

Zebrafish Jagged 2 (JAG2) interaction partners

  1. Expression of both jagged2 and jagged1b mRNA in the central nervous system suggested that they might be involved in control of differentiating neural progenitors.

  2. Mice homozygous for a deletion in the Notch (show NOTCH1 Antibodies)-interaction domain of Jag2 presented a variety of severe dental abnormalities.

  3. Jagged and Delta ligands are functionally redundant or required in specific combinations in many differentiation processes

  4. Jag2-mediated Notch (show NOTCH1 Antibodies) signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord.

JAG2 Antigen Profile

Antigen Summary

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with JAG2

  • jagged 2 (JAG2) antibody
  • jagged 2 (jag2) antibody
  • jagged 2 (Jag2) antibody
  • jagged 2b (jag2b) antibody
  • D12Ggc2e antibody
  • HJ2 antibody
  • jag2 antibody
  • mJagged2-1 antibody
  • SER2 antibody
  • serB antibody
  • Serh antibody
  • sm antibody
  • zgc:152855 antibody

Protein level used designations for anti-Jagged 2 (JAG2) Antibodies

jagged 2 , protein jagged-2-like , protein jagged-2 , syndactylism , C-Serrate-2 , notch ligand , serrate-2 , serrateB , unp1068

GENE ID SPECIES
100014054 Monodelphis domestica
100447370 Pongo abelii
100497180 Xenopus (Silurana) tropicalis
100552963 Anolis carolinensis
16450 Mus musculus
3714 Homo sapiens
29147 Rattus norvegicus
776138 Gallus gallus
490882 Canis lupus familiaris
100522743 Sus scrofa
517405 Bos taurus
140422 Danio rerio
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