Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

JAG2 antibody (N-Term)

JAG2 Reactivity: Human, Mouse, Rat, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782165
  • Target See all JAG2 Antibodies
    JAG2 (Jagged 2 (JAG2))
    Binding Specificity
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 52
    • 25
    • 22
    • 6
    • 5
    • 5
    • 2
    Human, Mouse, Rat, Pig
    Host
    • 48
    • 5
    • 1
    Rabbit
    Clonality
    • 47
    • 7
    Polyclonal
    Conjugate
    • 23
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAG2 antibody is un-conjugated
    Application
    • 50
    • 21
    • 20
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    RAQGRGRLPR RLLLLLALWV QAARPMGYFE LQLSALRNVN GELLSGACCD
    Predicted Reactivity
    Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against JAG2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human JAG2
    Top Product
    Discover our top product JAG2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1238 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Passos Gregorio, Gattaz, Tavares, Kieling, Timm, Wang, Berg Rasmussen, Werge, Dias-Neto: "Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects." in: Schizophrenia research, Vol. 88, Issue 1-3, pp. 275-82, (2006) (PubMed).

  • Target
    JAG2 (Jagged 2 (JAG2))
    Alternative Name
    JAG2 (JAG2 Products)
    Synonyms
    D12Ggc2e antibody, Serh antibody, mJagged2-1 antibody, sm antibody, HJ2 antibody, SER2 antibody, jag2 antibody, serB antibody, zgc:152855 antibody, jagged 2 antibody, jagged 2b antibody, JAG2 antibody, jag2 antibody, Jag2 antibody, jag2b antibody
    Background
    The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: HJ2, SER2
    Protein Interaction Partner: GFI1B, ATN1, ATXN7, CACNA1A, MIB2, NOTCH3, NOTCH2, NOTCH1,
    Protein Size: 1238
    Molecular Weight
    130 kDa
    Gene ID
    3714
    NCBI Accession
    NM_002226, NP_002217
    UniProt
    Q9Y219
    Pathways
    Notch Signaling, Sensory Perception of Sound
You are here:
Support