JAG2 antibody (C-Term)

Catalog No. ABIN390090

Cited in 1 publication. The Rabbit Polyclonal anti-JAG2 antibody (Clone RB1913-1914) (ABIN390090) specifically detects JAG2 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for JAG2 antibody (C-Term) (ABIN390090)

Target: JAG2 (Jagged 2 (JAG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1913-1914

Product Details anti-JAG2 Antibody

Binding Specificity: AA 1209-1238, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Jagged 2 (JAG2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1238 amino acids from the C-terminal region of human Jagged 2 (JAG2).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-JAG2 antibody (ABIN390090)

Yao, Guihard, Blazquez-Medela, Guo, Liu, Boström, Yao: "Matrix Gla protein regulates differentiation of endothelial cells derived from mouse embryonic stem cells." in: Angiogenesis, Vol. 19, Issue 1, pp. 1-7, (2016) (PubMed).

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Background: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.

Molecular Weight: 133367

Gene ID: 3714

NCBI Accession: NP_002217, NP_660142

UniProt: Q9Y219

Pathways: Notch Signaling, Sensory Perception of Sound