Isoleucyl-tRNA Synthetase (IARS) Peptide
IARS
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936037
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Isoleucyl-tRNA Synthetase (IARS) Peptide (ABIN936037)
Target
IARS
(Isoleucyl-tRNA Synthetase (IARS))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IARS antibody,
Alternative Names: IARS control peptide, IARS antibody Blocking Peptide, Anti-IARS Blocking Peptide, Isoleucyl-tRNA Synthetase Blocking Peptide, FLJ20736 Blocking Peptide, IARS1 Blocking Peptide, ILRS Blocking Peptide, PRO0785 Blocking Peptide -
Purification
- Affinity chromatography using phosphopeptide and cross-adsorbed with the corresponding non-phosphopeptide.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- IARS (Isoleucyl-tRNA Synthetase (IARS))
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Background
- Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
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Molecular Weight
- 144 kDa
Target
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