Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptide
IARS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978371
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptide (ABIN978371)
Target
IARS
(Isoleucyl-tRNA Synthetase (IARS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-IARS Antibody(ARP54954_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- IARS (Isoleucyl-tRNA Synthetase (IARS))
-
Background
-
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: AR,EPRS,GARS,AIMP2,AKTIP,BCAR3,EPRS,GARS,GSTK1,MAGED1,MCC,SGK1,SNCA,TRAF6,TSC22D1,USP19,VHL
Protein Size: 1262 -
Molecular Weight
- 144 kDa
-
Gene ID
- 3376
-
NCBI Accession
- NM_013417, NP_038203
-
UniProt
- P41252
Target
-
You are here:
