Methionyl Aminopeptidase 2 (METAP2) Peptide
Quick Overview for Methionyl Aminopeptidase 2 (METAP2) Peptide (ABIN936942)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- ATGKKKKKKK KKRGPKVQTD PPSVPICDLY PNGVFPKGQE CEYPPTQDGR
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of METAP2 antibody,
Alternative Names: METAP2 control peptide, METAP2 antibody Blocking Peptide, Anti-METAP2 Blocking Peptide, Methionyl Aminopeptidase 2 Blocking Peptide, MAP2 Blocking Peptide, MNPEP Blocking Peptide, p67 Blocking Peptide, p67eIF2 Blocking Peptide, METAP2, METAP-2, METAP 2, METAP-2 Blocking Peptide, METAP 2 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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Background
- METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.
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Molecular Weight
- 53 kDa
Target
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