Glutaminyl-tRNA Synthetase (QARS) Peptide
Quick Overview for Glutaminyl-tRNA Synthetase (QARS) Peptide (ABIN937521)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- DQTLSLMEQL RGEALKFHKP GENYKTPGYV VTPHTMNLLK QHLEITGGQV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of QARS antibody,
Alternative Names: QARS control peptide, QARS antibody Blocking Peptide, Anti-QARS Blocking Peptide, glutaminyl-tRNA synthetase Blocking Peptide, GLNRS Blocking Peptide, PRO2195 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- QARS (Glutaminyl-tRNA Synthetase (QARS))
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Background
- Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
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Molecular Weight
- 88 kDa
Target
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