Glutaminyl-tRNA Synthetase (QARS) (N-Term) Peptide
Quick Overview for Glutaminyl-tRNA Synthetase (QARS) (N-Term) Peptide (ABIN982513)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- DQTLSLMEQL RGEALKFHKP GENYKTPGYV VTPHTMNLLK QHLEITGGQV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-QARS Antibody(ARP56628_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- QARS (Glutaminyl-tRNA Synthetase (QARS))
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Background
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
Alias Symbols: GLNRS, PRO2195
Protein Interaction Partner: ASL,CPNE3,DUSP11,MAP3K5,PRRC2A,RARS,RNF11,SMAD9,TRAF2,AIMP2,ASL,CPNE3,DUSP11,MAP3K5,PRRC2A,RARS,TRAF2
Protein Size: 775 -
Molecular Weight
- 88 kDa
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Gene ID
- 5859
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NCBI Accession
- NM_005051, NP_005042
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UniProt
- P47897
Target
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