H2A Histone Family, Member Y2 (H2AFY2) Peptide
Quick Overview for H2A Histone Family, Member Y2 (H2AFY2) Peptide (ABIN939851)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- KKGGKKSKAA KPRTSKKSKP KDSDKEGTSN STSEDGPGDG FTILSSKSLV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of H2 AFY2 antibody,
Alternative Names: H2AFY2 control peptide, H2AFY2 antibody Blocking Peptide, Anti-H2AFY2 Blocking Peptide, H2A Histone Y2 Blocking Peptide, macroH2A2 Blocking Peptide, H2AF, HAF-2, HAF 2, HAF-2 Blocking Peptide, HAF 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Background
- H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
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Molecular Weight
- 40 kDa
Target
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