H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptide
H2AFY2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977826
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptide (ABIN977826)
Target
H2AFY2
(H2A Histone Family, Member Y2 (H2AFY2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PRIHPELLAK KRGTKGKSET ILSPPPEKRG RKATSGKKGG KKSKAAKPRT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-H2AFY2 Antibody(ARP57281_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Background
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H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Alias Symbols: macroH2A2
Protein Interaction Partner: tat
Protein Size: 372 -
Molecular Weight
- 40 kDa
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Gene ID
- 55506
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NCBI Accession
- NM_018649, NP_061119
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UniProt
- Q9P0M6
Target
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