TNFRSF11A Protein (AA 28-202) (His tag)
Quick Overview for TNFRSF11A Protein (AA 28-202) (His tag) (ABIN7479633)
Target
See all TNFRSF11A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 28-202
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Purification tag / Conjugate
- This TNFRSF11A protein is labelled with His tag.
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Sequence
- MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
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Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (His-DYKDDDDK-Strep II Tag)
TNFRSF11A Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-214) (Active) protein (hFc Tag)TNFRSF11A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-130) protein (GST tag)TNFRSF11A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (Fc Tag)TNFRSF11A Origin: Rat Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) protein (His tag)TNFRSF11A Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) protein (Fc Tag)TNFRSF11A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-202) protein (His-IF2DI Tag)TNFRSF11A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-212) protein (hIgG-His-tag)TNFRSF11A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) (Active) protein (Fc Tag)TNFRSF11A Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS (PH: 8.0), 50% glycerin
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Storage
- 4 °C
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- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Alternative Name
- Tumor necrosis factor receptor superfamily member 11A
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Background
- Background: RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate na?ve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues). Synonyms: Osteoclast differentiation factor receptor Short name=ODFR Receptor activator of NF-KB CD_antigen=CD265.
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Molecular Weight
- 23.3 kD
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UniProt
- Q9Y6Q6
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Pathways
- NF-kappaB Signaling
Target
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