Aprotinin Protein (Aprotinin)
This Native Aprotinin protein is expressed in Cow.
Catalog No. ABIN620215
$485.30
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Quick Overview for Aprotinin Protein (Aprotinin) (ABIN620215)
Target
See all Aprotinin Proteins
Aprotinin
Protein Type
Native
Origin
Cow
Source
Cow
Purity
> 98.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
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Characteristics
- Native Bovine Aprotinin
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- The protein (1 mg/ml) was lyophilized with no additives.It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M omega cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
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Storage
- -20 °C
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- Aprotinin
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Alternative Name
- Aprotinin
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Background
- Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7 } arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512. Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b). Synonyms: Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP.
Target
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