PDGF-AA Homodimer Protein
This Recombinant PDGF-AA Homodimer protein is expressed in not_set.
Catalog No. ABIN624786
$239.20
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
Quick Overview for PDGF-AA Homodimer Protein (ABIN624786)
Target
PDGF-AA Homodimer
Protein Type
Recombinant
Origin
Human
Host
Please inquire
Purity
> 97.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
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Sequence
- The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ile-Glu-Glu-Ala.
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Characteristics
- Recombinant Human Platelet Derived Growth Factor-AA
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PDGF-AA Homodimer protein
Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- The protein was lyophilized with no additives.It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AA in sterile 18M -cm H 2 O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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Storage
- -20 °C
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- PDGF-AA Homodimer
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Alternative Name
- Platelet-Derived Growth Factor AA
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Background
- Platelet-Derived Growth Factor AA Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 125 amino acids and having a total molecular mass of 28511 Dalton. PDGF-AA is purified by proprietary chromatographic techniques. Introduction: PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Synonyms: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.
Target
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