PDGF-AA Homodimer Protein
-
- Target
- PDGF-AA Homodimer
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Yeast (Pichia pastoris)
- Purpose
- Recombinant Human PDGF-AA Protein
- Sequence
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- Specificity
- Ser87-Thr211
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- 600.1EU/μg
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.17 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
- Target
- PDGF-AA Homodimer
- Alternative Name
- PDGF-AA
- Synonyms
- PDGF-A Protein, PDGF1 Protein, AA409063 Protein, CD142 Protein, Cf-3 Protein, Cf3 Protein, TF Protein, PDGFACP Protein, platelet derived growth factor subunit A Protein, coagulation factor III Protein, platelet derived growth factor, alpha Protein, PDGFA Protein, F3 Protein, Pdgfa Protein
- Background
-
Description: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
Name: PDGF1, PDGF-A
- Gene ID
- 5154
- UniProt
- P04085
-