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PDGF-AA Homodimer Protein

Origin: Human Host: Yeast (Pichia pastoris) Recombinant
Catalog No. ABIN7536482
  • Target
    PDGF-AA Homodimer
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 2
    Human
    Source
    • 10
    • 1
    Yeast (Pichia pastoris)
    Purpose
    Recombinant Human PDGF-AA Protein
    Sequence
    SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
    Specificity
    Ser87-Thr211
    Sterility
    0.22 μm filtered
    Endotoxin Level
    600.1EU/μg
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Concentration
    0.17 mg/mL
    Buffer
    Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    PDGF-AA Homodimer
    Alternative Name
    PDGF-AA
    Synonyms
    PDGF-A Protein, PDGF1 Protein, AA409063 Protein, CD142 Protein, Cf-3 Protein, Cf3 Protein, TF Protein, PDGFACP Protein, platelet derived growth factor subunit A Protein, coagulation factor III Protein, platelet derived growth factor, alpha Protein, PDGFA Protein, F3 Protein, Pdgfa Protein
    Background

    Description: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.

    Name: PDGF1, PDGF-A

    Gene ID
    5154
    UniProt
    P04085
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