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IFNA2 Protein

This Recombinant IFNA2 protein is produced in not_set.
Catalog No. ABIN623781
$1,109.75
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for IFNA2 Protein (ABIN623781)

Target

See all IFNA2 Proteins
IFNA2 (Interferon, alpha 2 (IFNA2))

Protein Type

Recombinant

Origin

  • 21
  • 5
  • 1
  • 1
  • 1
Human

Host

Please inquire

Purity

> 98.0 % as determined by both (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • Sequence

    The sequence of the first five N-terminal amino acids was determined and was found to be Cys-Asp-Leu-Pro-Gln, conforming to the sequence of native human IFN-a. N-terminal methionine has been completely removed enzymatica lly.

    Characteristics

    Recombinant Human Interferon-alpha-2a
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.924 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program

    Buffer

    Lyophilized without additives.It is recommended to reconstitute the lyophilized Interferon-alpha 2a in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Reconstitute at 0.1 mg/ml with 5mM NaAcetate, pH-6.

    Storage

    -20 °C
  • Target

    IFNA2 (Interferon, alpha 2 (IFNA2))

    Alternative Name

    Interferon-alpha-2a

    Background

    Interferon Alpha Human 2a Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The Interferon-a 2a gene was obtained from human leukocytes. The IFN-A 2a is purified by proprietary chromatographic techniques. Introduction: IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase. Synonyms: Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-alpha 2a.

    Pathways

    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
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