IFNA2 Protein
Quick Overview for IFNA2 Protein (ABIN623781)
Target
See all IFNA2 ProteinsProtein Type
Origin
Host
Purity
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Sequence
- The sequence of the first five N-terminal amino acids was determined and was found to be Cys-Asp-Leu-Pro-Gln, conforming to the sequence of native human IFN-a. N-terminal methionine has been completely removed enzymatica lly.
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Characteristics
- Recombinant Human Interferon-alpha-2a
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.924 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program
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Buffer
- Lyophilized without additives.It is recommended to reconstitute the lyophilized Interferon-alpha 2a in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Reconstitute at 0.1 mg/ml with 5mM NaAcetate, pH-6.
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Storage
- -20 °C
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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Alternative Name
- Interferon-alpha-2a
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Background
- Interferon Alpha Human 2a Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The Interferon-a 2a gene was obtained from human leukocytes. The IFN-A 2a is purified by proprietary chromatographic techniques. Introduction: IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase. Synonyms: Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-alpha 2a.
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
Target
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