Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CCL3 Protein

This Recombinant CCL3 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN935631
$784.75
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 16 to 22 Business Days

Quick Overview for CCL3 Protein (ABIN935631)

Target

See all CCL3 Proteins
CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 16
  • 11
  • 7
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 26
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA

    Characteristics

    Purified recombinant Human MIP1 alpha protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration of 50.0-100.0 ng/mL.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
  • Want other Options for this Protein ?

    !
    Discover Our Predefined Custom Proteins and Custom Protein Services!

    Your project requires further customization? Contact us and discover our custom protein solutions

  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

    Buffer

    Supplied as a lyophilized powder.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

    Alternative Name

    MIP1 alpha

    Background

    Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
    Alternative Names: MIP-1 alpha protein, LD78 beta protein, MIP 1 alpha, CCL3 protein, MIP 1 alpha protein, MIP-1 alpha protein, MIP-1 alpha, Macrophage Inflammatory Protein-1 alpha protein, MIP1 alpha

    Molecular Weight

    7.8 kDa

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Autophagy
You are here:
Blank Blank Blank Blank
Blank Blank Blank Blank
Chat with us!