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Browse our PTK2B (PTK2B) ELISA Kits

Full name:
PTK2B Protein tyrosine Kinase 2 beta ELISA Kits (PTK2B)
On www.antibodies-online.com are 17 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) ELISA Kits from 6 different suppliers available. Additionally we are shipping PTK2B Antibodies (248) and PTK2B Proteins (9) and many more products for this protein. A total of 291 PTK2B products are currently listed.
Synonyms:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk
list all ELISA KIts Gene Name GeneID UniProt
PTK2B 24185 P47196
PTK2B 11651 P31750
PTK2B 2185 Q14289

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Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ambient fine particulate matter-induced myocarditis is mediated by EGFR/Akt signaling and overexpression of NLRP3 and NLRP12.

  2. GSK3b may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT (show AKT1 ELISA Kits) and possibly participating in the regulation of cell volume and excitability.

  3. Akt1 regulates cell division and F-actin rearrangement in mouse fertilized eggs.

  4. The results suggest that KCa3.1 (show KCNN4 ELISA Kits) activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling pathways.

  5. These results reveal a key role of the AKT (show AKT1 ELISA Kits)-GSK3beta-eIF2Bepsilon (show EIF2B5 ELISA Kits) signaling module in regulating axon regeneration in the adult mammalian central nervous system.

  6. IL-4 (show IL4 ELISA Kits) signaling co-opts the Akt (show AKT1 ELISA Kits)-mTORC1 pathway to regulate Acly (show ACLY ELISA Kits), a key enzyme in acetyl-CoA (show LPCAT1 ELISA Kits) synthesis, leading to increased histone acetylation and macrophage gene induction.

  7. Data suggest that phosphorylated Ser473-Akt akt (show AKT1 ELISA Kits) proto-oncogene (show RAB1A ELISA Kits) protein may be a potential player in the major zygotic genome activation (ZGA) of 2-cell embryos.

  8. PI3K-Akt (show AKT1 ELISA Kits)-Foxo1 (show FOXO1 ELISA Kits) and mTORC1-mTORC2 (show CRTC2 ELISA Kits) pathways differentially regulate endothelial cell elongation.

  9. suppression of AKT (show AKT1 ELISA Kits) by hyperactivation of mTORC1, inhibition on nuclear ERalpha (show ESR1 ELISA Kits) signaling, and down-regulation of cell-cycle-driving proteins play important roles in the retarded mammary development induced by Tsc1 (show TSC1 ELISA Kits) deletion.

  10. results suggest that emodin inhibited apoptosis and autophagy in TNF-alpha (show TNF ELISA Kits)-induced myoblasts through the activation of phosphorylated Akt (show AKT1 ELISA Kits)

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Studies suggest that PYK2 is a common downstream effector of ErbB (show EGFR ELISA Kits) and IL8 (show IL8 ELISA Kits) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  2. Pyk2 is a key downstream signaling molecules of CCR7 (show CCR7 ELISA Kits) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  3. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  4. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (show LPXN ELISA Kits).

  5. Src (show SRC ELISA Kits) has a role in priming Pyk2 (but not FAK (show PTK2 ELISA Kits)) phosphorylation and subsequent activation downstream of integrins

  6. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  7. FAK (show PTK2 ELISA Kits) and PYK2 functioned redundantly to promote the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway by phosphorylating GSK3beta(Y216) to reinforce pathway output-beta-catenin (show CTNNB1 ELISA Kits) accumulation and intestinal tumorigenesis.

  8. This study identified Pyk2 as a cellular component required for the intracellular trafficking of HPV16 during infection.

  9. These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via reactive oxygen species-alphavbeta3 integrin-FAK (show PTK2 ELISA Kits)/Pyk2 signaling pathways.

  10. data suggest a novel role for FAK (show PTK2 ELISA Kits) in GPVI (show GP6 ELISA Kits)-dependent ROS (show ROS1 ELISA Kits) formation and platelet activation and elucidate a proximal signaling role for FAK (show PTK2 ELISA Kits) within the GPVI (show GP6 ELISA Kits) pathway.

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Elisa Kit
  • thymoma viral proto-oncogene 1 (Akt1) Elisa Kit
  • protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • protein tyrosine kinase 2 beta (Ptk2b) Elisa Kit
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) Elisa Kit
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) Elisa Kit
  • Akt Elisa Kit
  • CADTK Elisa Kit
  • CAKB Elisa Kit
  • CAKbeta Elisa Kit
  • E430023O05Rik Elisa Kit
  • FADK2 Elisa Kit
  • FAK2 Elisa Kit
  • PKB Elisa Kit
  • PKB/Akt Elisa Kit
  • PKBalpha Elisa Kit
  • PTK Elisa Kit
  • Pyk2 Elisa Kit
  • Rac Elisa Kit
  • Raftk Elisa Kit

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
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