Browse our Primase, DNA, Polypeptide 2 (58kDa) Proteins (PRIM2)

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Primase, DNA, Polypeptide 2 (58kDa) Proteins (PRIM2)
On are 5 Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) Proteins from 4 different suppliers available. Additionally we are shipping Primase, DNA, Polypeptide 2 (58kDa) Antibodies (39) and Primase, DNA, Polypeptide 2 (58kDa) Kits (7) and many more products for this protein. A total of 53 Primase, DNA, Polypeptide 2 (58kDa) products are currently listed.
AI323589, p58, Pola3, PRIM2A
list all proteins Gene Name GeneID UniProt
PRIM2 19076 P33610
PRIM2 301323  
PRIM2 5558 P49643

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Primase, DNA, Polypeptide 2 (58kDa) Proteins (PRIM2) by Origin

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More Proteins for Primase, DNA, Polypeptide 2 (58kDa) Interaction Partners

Human Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) interaction partners

  1. Data suggest that PRIM1 (show PRIM1 Proteins)-p58 (show CDK11B Proteins),C-terminal domain stays bound to initiating NTP and 3prime-overhang DNA during whole cycle of RNA primer synthesis; meanwhile, PRIM1-p49 (show PRIM1 Proteins) slides along DNA template toward 5prime-end with PRIM1 (show PRIM1 Proteins)-p58 (show CDK11B Proteins),N-terminal domain attached.

  2. the N-terminal domain of the large subunit of primase (p58N) directly interacts with the C-terminal domain of the catalytic subunit of polalpha (p180C)

  3. PRIM2 gene is not imprinted in the placenta.

  4. The fragment that forms a beta (show SUCLA2 Proteins)-sheet in the reported structure p58C/3L9Q of the same human primase domain is folded in three alpha-helices in our p58C/3Q36 structure, similarly to yeast primase.

  5. analysis of the iron-sulfur cluster in the C-terminal domain of the p58 (show CDK11B Proteins) subunit of human DNA primase

Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) Protein Profile

Protein Summary

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit.

Alternative names and synonyms associated with Primase, DNA, Polypeptide 2 (58kDa) (PRIM2)

  • primase, DNA, polypeptide 2 (58kDa) (prim2)
  • DNA primase, p58 subunit (Prim2)
  • primase, DNA, polypeptide 2 (Prim2)
  • primase, DNA, polypeptide 2 (58kDa) (PRIM2)
  • AI323589 protein
  • p58 protein
  • Pola3 protein
  • PRIM2A protein

Protein level used designations for PRIM2

DNA primase, p58 subunit , DNA primase 58 kDa subunit , DNA primase large subunit , DNA polymerase alpha subunit III (primase) , p58 , DNA primase subunit p58 , dJ422B11.1.1 , primase polypeptide 2A, 58kDa , primase, polypeptide 2A, 58kDa , DNA primase polypeptide 2

548762 Xenopus (Silurana) tropicalis
19076 Mus musculus
301323 Rattus norvegicus
5558 Homo sapiens
474950 Canis lupus familiaris
514682 Bos taurus
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