anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11) Antibodies

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11) interaction partners

1. here were significant differences in SNPs at rs1256061 of estrogen receptor beta gene and rs17822931, rs16945916 and rs62058521 in ABCC11 gene between the axillary osmidrosis patients and normal people

2. the differential expression pattern of ABCC11 and ABCB5 genes may serve as outliers, potentially associated with incidence of multifocal/multicentric breast cancer

3. The previous findings of a previously unreported homozygous genotype for both the Delta27 and A alleles suggest that the Delta27 deletion might have occurred in the A allele of ABCC11 gene with the 538G>A mutation.

4. our study has provided conclusive evidence for the association of rs17822931 in the ABCC11 with the susceptibility of AO in the Chinese Han population

5. Serum levels of MRP8/MRP14 and MRP6 were up-regulated in patients with Graves' disease (GD) and Hashimoto's thyroiditis (HT). In addition, mRNA expression of MRP proteins in PBMCs and the thyroid gland was markedly elevated in these patients.

6. High MRP8 expression is associated with Rheumatoid Arthritis.

7. ABCC11 c.1637C>T polymorphisms affects fluoropyrimidine toxicity to leukocytes

8. Our results confirmed the association between NAF yield and earwax phenotype through ABCC11 genotype. Combined with the recency of last birth, ABCC11 genotype should be considered in the design of studies utilizing NAF as a biosample.

9. Tenofovir disoproxil fumarate is a new substrate of ABCC11.

10. These results suggest that N-linked glycosylation is important for the protein stability of ABCC11, and physiological alteration in glucose may affect the ABCC11 protein level and ABCC11-related phenotypes in humans, such as axillary osmidrosis.

11. The present study shows that the protein expression of ABCC10 significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients

12. ABCC11 protein was detected in the human axillary apocrine glands of the 538GG homozygote or 538GA heterozygote, not in the 538AA homozygote. These findings would contribute to a better understanding of the molecular basis of axillary osmidrosis.

13. No Association of the rs17822931 Polymorphism in ABCC11 was found with Breast Cancer Risk in Koreans.

14. Presents a simple isothermal genotyping method capable of detecting single nucleotide polymorphisms in the human ATP-binding cassette transporter ABCC11 gene and its application to the clinical diagnosis of axillary osmidrosis.

15. identified c.1637C>T (T546M), previously associated with 5-FU-related toxicity, as a novel functionally damaging ABCC11 variant exhibiting markedly reduced transport function of 5-FdUMP, the active cytotoxic metabolite of 5-FU. Detailed analysis of 14 subpopulations revealed highest allele frequencies of c.1637C>T in Europeans and Americans (up to 11%) compared with Africans and Asians (up to 3%).

16. The ABCC11 gene SNP of the 538 G>A allele was associated with a downregulation of the mRNA expression of ApoD in the apocrine glands, which may indicate a role for the ABCC11 gene in the mediation of osmidrosis

17. A single nucleotide polymorphism in ABCC11 affects the cerumen volatile organic compounds profiles of individuals from African, Caucasian, and Asian descent.

18. role in the generation of axillary malodour

19. ABCC11 gene SNP results in lower levels of axillary odour in the A/A homozygotes, but A/A subjects still produce noticeable amounts of axillary odour. Axillary skin metabolites/bacterial genera/personal hygiene behaviours are also influenced by this SNP.

20. The rs17822931 SNP in ABCC11 is associated with wet earwax and bromhidrosis in a chinese family.