anti-Actin Filament Associated Protein 1 (AFAP1) Antibodies

The protein encoded by AFAP1 is a Src binding partner. Additionally we are shipping AFAP Kits (14) and AFAP Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AFAP1 60312 Q8N556
AFAP1 70292 Q80YS6
AFAP1 140935 Q8VH46
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Top anti-AFAP Antibodies at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AFAP1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Liver Host: Rabbit Target Name: AFAP1 Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB AFAP1 Antibody (C-term) (ABIN656677) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the AFAP1 antibody detected the AFAP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB AFAP1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane).This demonstrates the AFAP1 antibody detected the AFAP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: AFAP Antibody [NBP1-90216] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: AFAP Antibody [NBP1-90216] - Staining of human cell line U-251MG shows positivity in cytoplasm, cytoskeleton (actin filaments) & focal adhesions. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-AFAP1 / AFAP antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using AFAP1 antibody (ABIN1870854) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. 100 μL Log in to see 16 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of AFAP1 in Hela cell lysate with AFAP1 antibody at (A) 1 and (B) 2 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lymphoma tissue labeled with Anti-AFAP/AFAP-110 Polyclonal Antibody, Unconjugated (ABIN1387171) at 1:200 followed by conjugation to the secondary antibody 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 4 to 8 Days
$522.50
Details

Top referenced anti-AFAP Antibodies

  1. Human Monoclonal AFAP Primary Antibody for CyTOF, ELISA - ABIN4278565 : Chan, Tan, Sng, Teo, Phua, Choo, Li, Zhu, Tan: Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress. in Cell death & disease 2017 (PubMed)

More Antibodies against AFAP Interaction Partners

Human Actin Filament Associated Protein 1 (AFAP1) interaction partners

  1. Authors determined that AFAP1-AS1 functions as a competing endogenous RNA in NPC to regulate the Rho/Rac pathway through miR-423-5p.

  2. The observed up-regulation of AFAP1-AS1 in tumor samples compared with ANCTs implies its involvement in breast cancer pathogenesis and potentiates it as a biomarker or therapeutic target.

  3. The high LncRNA AFAP1-AS1 expression was significantly related to advanced clinical stage, larger tumor size, earlier tumor metastasis, earlier lymph nodal involvement and vascular invasion. High LncRNA AFAP1-AS1 expression was an unfavorable prognostic factor in various cancers.

  4. AFAP-1 is a key mediator in the inflammatory signaling-induced, translocation-independent attenuation of P-glycoprotein efflux in brain capillary endothelial cells.

  5. The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE).

  6. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS).

  7. Methylation of the long noncoding RNA AFAP1-AS1 is reduced in BE and EAC, and its expression inhibits cancer-related biologic functions of EAC cells.

  8. AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB 231 breast cancer cells.

Mouse (Murine) Actin Filament Associated Protein 1 (AFAP1) interaction partners

  1. These data define, for the first time, the requirement of AFAP1 for the spatial and temporal regulation of cSrc activity in the normal breast, specifically for milk production.

  2. In E16 mouse embryos, AFAP expression levels concentrated in the olfactory bulb, cortex, forebrain, cerebellum, and various peripheral sensory structures.In P3 mouse pups, overall expression was reduced. (AFAP-110)

  3. Data suggest that one major function of AFAP-110 is to relay signals from protein kinase C alpha that direct the activation of c-Src and the formation of podosomes.

  4. Actin filament associated protein-110 (AFAP) colocalizes with cSrc to promote cSrc activation and cell migration.

  5. AFAP120 may coordinate Src signaling with the dynamic changes in the actin cytoskeleton that drive growth cone motility and axon elongation.

  6. These results indicate that AFAP120 plays a role in organizing dynamic actin structures during neuronal differentiation and suggest that AFAP120 may help regulate the transition from motile precursor to morphologically differentiated neurons.

AFAP (AFAP1) Antigen Profile

Protein Summary

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AFAP1

  • actin filament associated protein 1 (AFAP1) antibody
  • actin filament associated protein 1 (afap1) antibody
  • actin filament associated protein 1 (Afap1) antibody
  • 2600003E23Rik antibody
  • 9630044L16Rik antibody
  • Afap antibody
  • AFAP-110 antibody
  • AFAP110 antibody
  • AI848729 antibody
  • mKIAA3018 antibody

Protein level used designations for AFAP1

actin filament associated protein 1 , actin filament-associated protein 1-like , 110 kDa actin filament-associated protein , actin filament-associated protein 1 , actin filament-associated protein, 110 kDa , AFAP-110 , neural actin filament protein , pp110

GENE ID SPECIES
461111 Pan troglodytes
779522 Xenopus (Silurana) tropicalis
100014539 Monodelphis domestica
100056653 Equus caballus
100454152 Pongo abelii
100466777 Ailuropoda melanoleuca
60312 Homo sapiens
70292 Mus musculus
140935 Rattus norvegicus
100735141 Cavia porcellus
100522448 Sus scrofa
374034 Gallus gallus
488786 Canis lupus familiaris
534032 Bos taurus
101109449 Ovis aries
100339958 Oryctolagus cuniculus
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